The molecular mechanism of action of artemisinin--the debate continues.
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Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparumTraditional medicines and globalization: current and future perspectives in ethnopharmacologyHaem-activated promiscuous targeting of artemisinin in Plasmodium falciparumSupergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunateA Partial Convergence in Action of Methylene Blue and Artemisinins: Antagonism with Chloroquine, a Reversal with Verapamil, and an Insight into the Antimalarial Activity of ChloroquineRearrangements of organic peroxides and related processesArtemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasitesRecent advances in understanding apicomplexan parasitesSesquiterpene Lactones from Artemisia Genus: Biological Activities and Methods of AnalysisChemical biology approaches for the study of apicomplexan parasitesModulation of PF10_0355 (MSPDBL2) alters Plasmodium falciparum response to antimalarial drugsSmall molecule screen for candidate antimalarials targeting Plasmodium Kinesin-5Endoperoxide antimalarials: development, structural diversity and pharmacodynamic aspects with reference to 1,2,4-trioxane-based structural scaffoldArtemisinin Action and Resistance in Plasmodium falciparumArtesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and non-caspase apoptosisThe activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasitesP. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-actionPrediction of the P. falciparum target space relevant to malaria drug discoveryAnti-plasmodial polyvalent interactions in Artemisia annua L. aqueous extract--possible synergistic and resistance mechanismsAnticancer properties of distinct antimalarial drug classesTargeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistanceInhibition of an Erythrocyte Tyrosine Kinase with Imatinib Prevents Plasmodium falciparum Egress and Terminates ParasitemiaNew Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics.Plasmodium falciparum K13 Mutations Differentially Impact Ozonide Susceptibility and Parasite Fitness In Vitro.Differential effect of artemisinin against cancer cell lines.Targeting iron metabolism in drug discovery and deliveryReactions of antimalarial peroxides with each of leucomethylene blue and dihydroflavins: flavin reductase and the cofactor model exemplified.Untargeted Proteomics and Systems-Based Mechanistic Investigation of Artesunate in Human Bronchial Epithelial Cells.Expanding the Antimalarial Drug Arsenal-Now, But How?Identification of intracellular and plasma membrane calcium channel homologues in pathogenic parasites.Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C.Natural products: a continuing source of novel drug leadsEmerging artemisinin resistance in the border areas of Thailand.Dihydroartemisinin exerts its anticancer activity through depleting cellular iron via transferrin receptor-1.Efficient and stereocontrolled synthesis of 1,2,4-trioxolanes useful for ferrous iron-dependent drug delivery.Genetic diversity and lack of artemisinin selection signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion.Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.Artemisinins, new miconazole potentiators resulting in increased activity against Candida albicans biofilms.Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion.Syntheses and biological studies of marine terpenoids derived from inorganic cyanide.
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The molecular mechanism of action of artemisinin--the debate continues.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 March 2010
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vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
The molecular mechanism of action of artemisinin--the debate continues.
@en
The molecular mechanism of action of artemisinin--the debate continues.
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type
label
The molecular mechanism of action of artemisinin--the debate continues.
@en
The molecular mechanism of action of artemisinin--the debate continues.
@nl
prefLabel
The molecular mechanism of action of artemisinin--the debate continues.
@en
The molecular mechanism of action of artemisinin--the debate continues.
@nl
P1433
P1476
The molecular mechanism of action of artemisinin--the debate continues
@en
P2093
Paul M O'Neill
Victoria E Barton
P304
P356
10.3390/MOLECULES15031705
P407
P50
P577
2010-03-12T00:00:00Z