Leptin-promoted cilia assembly is critical for normal energy balance
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Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice.Leptin Elongates Hypothalamic Neuronal Cilia via Transcriptional Regulation and Actin DestabilizationThe BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane.Type 3 Adenylyl Cyclase and Somatostatin Receptor 3 Expression Persists in Aged Rat Neocortical and Hippocampal Neuronal Cilia.Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice.Dysfunction of intraflagellar transport-A causes hyperphagia-induced obesity and metabolic syndrome.The Leptin Receptor Complex: Heavier Than Expected?Metabolic regulation and energy homeostasis through the primary Cilium.Bardet-Biedl syndrome: Is it only cilia dysfunction?Leptin signalling pathways in hypothalamic neurons.KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability.The cilium: a cellular antenna with an influence on obesity risk.Primary Cilia in Cystic Kidney Disease.New Roles of the Primary Cilium in Autophagy.Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neuronsWDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome.The role of primary cilia in obesity and diabetes.Signaling through the Primary Cilium.Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.Primary Cilia as a Signaling Platform for Control of Energy Metabolism.
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P2860
Leptin-promoted cilia assembly is critical for normal energy balance
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 25 March 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Leptin-promoted cilia assembly is critical for normal energy balance
@en
Leptin-promoted cilia assembly is critical for normal energy balance.
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type
label
Leptin-promoted cilia assembly is critical for normal energy balance
@en
Leptin-promoted cilia assembly is critical for normal energy balance.
@nl
prefLabel
Leptin-promoted cilia assembly is critical for normal energy balance
@en
Leptin-promoted cilia assembly is critical for normal energy balance.
@nl
P2093
P2860
P356
P1476
Leptin-promoted cilia assembly is critical for normal energy balance
@en
P2093
Bonghee Lee
Gil Myoung Kang
Hyun-Kyong Kim
Kyunghee Byun
Mi-Seon Shin
Min-Seon Kim
So Young Gil
P2860
P304
P356
10.1172/JCI69395
P407
P50
P577
2014-03-25T00:00:00Z