Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?
about
How SAMHD1 changes our view of viral restrictionSAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by VpxHIV restriction in quiescent CD4⁺ T cellsMolecular mechanisms of HIV immune evasion of the innate immune response in myeloid cellsHow SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest.Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase.Macrophage internal HIV-1 is protected from neutralizing antibodies.SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors.Differential effects of Vpr on single-cycle and spreading HIV-1 infections in CD4+ T-cells and dendritic cells.Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1.HERV-K(HML-2), a seemingly silent subtenant - but still waters run deep.HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic interventionViral determinants of HIV-1 macrophage tropism.Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophages.Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac.Preferential Destruction of Interstitial Macrophages over Alveolar Macrophages as a Cause of Pulmonary Disease in Simian Immunodeficiency Virus-Infected Rhesus MacaquesFunctional analysis of the relationship between Vpx and the restriction factor SAMHD1.Evidence for Vpr-dependent HIV-1 replication in human CD4+ CEM.NKR T-cells.Breaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives.Host restriction factors in retroviral infection: promises in virus-host interaction.Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supplyHIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.Expression Profiles of Vpx/Vpr Proteins Are Co-related with the Primate Lentiviral LineageIntracellular nucleotide levels and the control of retroviral infections.SIV vpx is essential for macrophage infection but not for development of AIDS.Cellular and Biochemical Mechanisms of the Retroviral Restriction Factor SAMHD1.SAMHD1: a new insight into HIV-1 restriction in myeloid cellsViral takeover of the host ubiquitin system.Restricted access to myeloid cells explained.Cellular restriction factors of feline immunodeficiency virus.Type I interferons as ambiguous modulators of chronic inflammation in the central nervous system.SAMHD1: a novel antiviral factor in intrinsic immunity.Lentivirus Vpr and Vpx accessory proteins usurp the cullin4-DDB1 (DCAF1) E3 ubiquitin ligase.Type I Interferon at the Interface of Antiviral Immunity and Immune Regulation: The Curious Case of HIV-1.DNA damage repair machinery and HIV escape from innate immune sensing.Journey to the heart of macrophages: the delicate relationship between HIV-1 and a multifaceted cell type.SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr).Vpr Enhances Tumor Necrosis Factor Production by HIV-1-Infected T Cells.G2/M cell cycle arrest correlates with primate lentiviral Vpr interaction with the SLX4 complex.The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.
P2860
Q24605899-EF8B3B9F-9A2B-4B65-A247-6043B1D60937Q24605940-FBB6A43C-50A3-45AB-835C-688B39AA9F05Q26995784-3DAA1E6B-B0C0-4537-A4CB-E97B8121659AQ27022978-A3C24E51-69E5-46D7-B6D1-2BE037B17580Q27693229-523F87E1-D4FE-42F6-A565-6BB7F89FDD7EQ29871440-F297F6E4-EE98-4624-9170-FDE8011DF0ECQ30510067-34E434D1-D83E-45E9-BBFD-4DC2586E438DQ34058234-119AD8C3-8EE0-4A3A-8DE5-0DD703D4FDBFQ34263217-355DA00D-140A-4DFE-A73F-21CEB07A9B19Q34312205-B6E50769-CA58-4D7E-AFBF-8AC6D7B13FC9Q34511101-85823745-C3F6-4D3D-9C86-7A194C454222Q34957142-751DA200-8B20-4AE1-A279-4AD67101D972Q35593158-545B1946-746E-46C6-9634-CC5BDA2C58BDQ35826158-FBD6847C-8A9D-47A6-A633-ECB20C58F62CQ36136752-B6651940-3641-49B9-84C5-95C8A67F8744Q36260388-2A5F70FB-86C1-46B4-9CF6-2B45B3679814Q36436068-6E04108C-7197-4A1B-8947-C2E7D4C41285Q36484010-0E88553A-5172-47B8-B35F-F1258034C1BAQ36537806-F1881419-14AA-437B-BC8D-7A89B6DA9FD4Q36548179-443ADB2E-21CB-4E4A-8C8D-9A918A53A7EEQ36690563-B74262DF-4E76-49B1-96D3-63F0FBB947E9Q36904912-DF9DFF0A-FB87-44B7-8BEC-365DDA84B132Q37146999-36E64C13-4A5D-4030-9CE4-8A27E982C2DAQ37244704-890CB9D6-E684-416D-A836-90D619133B3FQ37499154-9F35106A-C938-44EC-9B1A-69C6B11C1561Q37571689-30B3CBB0-C6C8-4053-868A-B5C3077550F1Q37899283-2D306490-A282-4183-BD98-0292A2C825AFQ37918803-54FD2638-CC61-4DA6-94BE-D85945C49FB2Q37945243-D441BF0A-4037-45C2-8CE2-188E7A90F586Q37954259-D68327F3-9E5A-4C04-9BEE-408B078C0F56Q38008369-169C1239-3173-43B0-8B96-BAC44743F3BFQ38041193-3F80B021-1502-49A3-9366-659DF8040CCCQ38051813-0D5E69E6-FED9-4D8C-B5D2-E967D4982A1DQ38181142-A942D3C3-5ED6-4D5E-8090-49076AC5CEACQ38209320-6805D5E3-D923-4516-B418-0456757C6A10Q38570360-4410F028-DA41-49D7-833A-E20476D4C5B6Q38761101-5E89E827-EFB6-4243-BA83-394EEE9367ECQ38832958-947F39AA-C732-48A0-994C-8589B112B339Q38947343-EB3518AB-9894-4C84-889B-55226804C810Q39405160-3A49738F-B102-4C1A-8FAE-8A85A470B4BE
P2860
Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 09 April 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Limelight on two HIV/SIV acces ...... ion: is Vpx overshadowing Vpr?
@en
Limelight on two HIV/SIV acces ...... ion: is Vpx overshadowing Vpr?
@nl
type
label
Limelight on two HIV/SIV acces ...... ion: is Vpx overshadowing Vpr?
@en
Limelight on two HIV/SIV acces ...... ion: is Vpx overshadowing Vpr?
@nl
prefLabel
Limelight on two HIV/SIV acces ...... ion: is Vpx overshadowing Vpr?
@en
Limelight on two HIV/SIV acces ...... ion: is Vpx overshadowing Vpr?
@nl
P2860
P921
P356
P1433
P1476
Limelight on two HIV/SIV acces ...... ion: is Vpx overshadowing Vpr?
@en
P2093
Catherine Transy
Diana Ayinde
P2860
P2888
P356
10.1186/1742-4690-7-35
P577
2010-04-09T00:00:00Z
P5875
P6179
1039211912