Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
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Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the Nrf2 pathwayThe importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current stateThe Nrf2/HO-1 Axis in Cancer Cell Growth and ChemoresistanceInterplay between cytosolic disulfide reductase systems and the Nrf2/Keap1 pathwayEvidence for beneficial effects of vitamin EHydrogen peroxide - production, fate and role in redox signaling of tumor cellsProtein degradation and the stress responseWhole grains, type 2 diabetes, coronary heart disease, and hypertension: links to the aleurone preferred over indigestible fiberThe haptoglobin-CD163-heme oxygenase-1 pathway for hemoglobin scavengingDo antioxidants impair signaling by reactive oxygen species and lipid oxidation products?Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondriaNrf2 Is an Attractive Therapeutic Target for Retinal DiseasesTrxR1 as a potent regulator of the Nrf2-Keap1 response systemDiscovery of direct inhibitors of Keap1-Nrf2 protein-protein interaction as potential therapeutic and preventive agentsA novel mechanism for cytoprotection against hypoxic injury: δ-opioid receptor-mediated increase in Nrf2 translocationThe clinical potential of influencing Nrf2 signaling in degenerative and immunological disordersMitochondria and reactive oxygen species: physiology and pathophysiologyInfluence of broccoli extract and various essential oils on performance and expression of xenobiotic- and antioxidant enzymes in broiler chickens.Crocin suppresses LPS-stimulated expression of inducible nitric oxide synthase by upregulation of heme oxygenase-1 via calcium/calmodulin-dependent protein kinase 4Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survivalVegetable and fruit juice enhances antioxidant capacity and regulates antioxidant gene expression in rat liver, brain and colon.Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy.Oxidative stress and inflammation modulate Rev-erbα signaling in the neonatal lung and affect circadian rhythmicity.Tissue-restricted expression of Nrf2 and its target genes in zebrafish with gene-specific variations in the induction profiles.Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks.Role of the Keap1/Nrf2 pathway in neurodegenerative diseases.Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism.Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapyLoss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicityActivation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells.Epigallocatechin-gallate stimulates NF-E2-related factor and heme oxygenase-1 via caveolin-1 displacement.Novel Nrf2 activators from microbial transformation products inhibit blood-retinal barrier permeability in rabbits.Di(2-ethylhexyl) phthalate-induced apoptosis in rat INS-1 cells is dependent on activation of endoplasmic reticulum stress and suppression of antioxidant protection.Keap1 expression has independent prognostic value in pancreatic adenocarcinomas3',4',5',5,7-pentamethoxyflavone sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathwayNRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages.Prognostic and predictive values of Nrf2, Keap1, p16 and E-cadherin expression in ovarian epithelial carcinoma.Cytoprotective Role of Nrf2 in Electrical Pulse Stimulated C2C12 Myotube.Activation of the Nrf2 Cell Defense Pathway by Ancient Foods: Disease Prevention by Important Molecules and Microbes Lost from the Modern Western Diet.Oxidant-induced cell death and Nrf2-dependent antioxidative response are controlled by Fra-1/AP-1
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Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 13 July 2010
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vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
@en
Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
@nl
type
label
Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
@en
Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
@nl
prefLabel
Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
@en
Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
@nl
P2093
P356
P1476
Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
@en
P2093
Junsei Mimura
Masayuki Yamamoto
P304
P356
10.1089/ARS.2010.3222
P577
2010-07-13T00:00:00Z