Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.
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Arginine deprivation therapy for malignant melanomaTargeting innate immunity for neurodegenerative disorders of the central nervous systemArginine Metabolism in Bacterial Pathogenesis and Cancer TherapyPotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesAmino acid deprivation using enzymes as a targeted therapy for cancer and viral infectionsSingle amino acid arginine deprivation triggers prosurvival autophagic response in ovarian carcinoma SKOV3The Combination of Arginine Deprivation and 5-Fluorouracil Improves Therapeutic Efficacy in Argininosuccinate Synthetase Negative Hepatocellular Carcinoma.Autophagic Mechanism in Anti-Cancer Immunity: Its Pros and Cons for Cancer Therapy.Bioengineered human arginase I with enhanced activity and stability controls hepatocellular and pancreatic carcinoma xenografts.Down-regulation of argininosuccinate synthetase is associated with cisplatin resistance in hepatocellular carcinoma cell lines: implications for PEGylated arginine deiminase combination therapy.Autophagy as a modulator and target in prostate cancer.Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.Arginine deiminase PEG20 inhibits growth of small cell lung cancers lacking expression of argininosuccinate synthetaseTargeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatinThe relationship of thioredoxin-1 and cisplatin resistance: its impact on ROS and oxidative metabolism in lung cancer cells.Negative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase.Evaluation of arginine deiminase treatment in melanoma xenografts using (18)F-FLT PET.Therapeutic interventions to disrupt the protein synthetic machinery in melanomaEpigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma.Enhanced autophagy in cytarabine arabinoside-resistant U937 leukemia cells and its potential as a target for overcoming resistance.Targeting nitric oxide signaling with nNOS inhibitors as a novel strategy for the therapy and prevention of human melanoma.BRAF inhibitor resistance enhances vulnerability to arginine deprivation in melanoma.TRAIL induces autophagic protein cleavage through caspase activation in melanoma cell lines under arginine deprivationRecombinant human arginase induced caspase-dependent apoptosis and autophagy in non-Hodgkin's lymphoma cellsA metabolic synthetic lethal strategy with arginine deprivation and chloroquine leads to cell death in ASS1-deficient sarcomas.Reduced argininosuccinate synthetase expression in refractory sarcomas: Impacts on therapeutic potential and drug resistance.Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes.Targeting autophagy during cancer therapy to improve clinical outcomes.The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy.Autophagy in the brains of young patients with poorly controlled T1DM and fatal diabetic ketoacidosis.Targeting arginine-dependent cancers with arginine-degrading enzymes: opportunities and challenges.The protein restriction mimetic Resveratrol is an autophagy inducer stronger than amino acid starvation in ovarian cancer cells.Targeting asparagine and autophagy for pulmonary adenocarcinoma therapy.Arginine deiminase: recent advances in discovery, crystal structure, and protein engineering for improved properties as an anti-tumor drug.Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20).Arginine dependence of tumor cells: targeting a chink in cancer's armor.Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancerThree-dimensional environment renders cancer cells profoundly less susceptible to a single amino acid starvation.Involvement of autophagy in recombinant human arginase-induced cell apoptosis and growth inhibition of malignant melanoma cells.Pseudolaric acid B induces caspase-dependent apoptosis and autophagic cell death in prostate cancer cells.
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P2860
Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.
@en
Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.
@nl
type
label
Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.
@en
Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.
@nl
prefLabel
Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.
@en
Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.
@nl
P2093
P2860
P1476
Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.
@en
P2093
P2860
P304
P356
10.2174/156652410791316995
P577
2010-06-01T00:00:00Z