Evaluation of therapeutic targets in animal models of arthritis: how does it relate to rheumatoid arthritis?
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T Cell Migration in Rheumatoid ArthritisA mouse model of adoptive immunotherapeutic targeting of autoimmune arthritis using allo-tolerogenic dendritic cellsA quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacyAnhuienoside C Ameliorates Collagen-Induced Arthritis through Inhibition of MAPK and NF-κB Signaling Pathways.Animal models of rheumatoid pain: experimental systems and insights.Adoptive Cell Therapy of Induced Regulatory T Cells Expanded by Tolerogenic Dendritic Cells on Murine Autoimmune Arthritis.Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis.Protective effect of Asarum extract in rats with adjuvant arthritis.A phase 2 randomized, double-blind study of AMG 108, a fully human monoclonal antibody to IL-1R, in patients with rheumatoid arthritisRodent preclinical models for developing novel antiarthritic molecules: comparative biology and preferred methods for evaluating efficacy.Role of tachykinin 1 and 4 gene-derived neuropeptides and the neurokinin 1 receptor in adjuvant-induced chronic arthritis of the mouseProteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis.Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis.Capsaicin-sensitive sensory nerves exert complex regulatory functions in the serum-transfer mouse model of autoimmune arthritis.Effect of methotrexate on collagen-induced arthritis assessed by micro-computed tomography and histopathological examination in female rats.Mobilization of natural killer cells inhibits development of collagen-induced arthritis.Expression of hedgehog signal pathway in articular cartilage is associated with the severity of cartilage damage in rats with adjuvant-induced arthritis.Preclinical Potency and Biodistribution Studies of an AAV 5 Vector Expressing Human Interferon-β (ART-I02) for Local Treatment of Patients with Rheumatoid Arthritis.Apoptotic Effect of Geniposide on Fibroblast-Like Synoviocytes in Rats with Adjuvant-Induced Arthritis via Inhibiting ERK Signal Pathway In Vitro.Micro-computed tomography evaluation and pathological analyses of female rats with collagen-induced arthritisApplying refinement to the use of mice and rats in rheumatoid arthritis research.Crude triterpenoid saponins from Anemone flaccida (Di Wu) exert anti-arthritic effects on type II collagen-induced arthritis in rats.Anti-Arthritic Activity of Schistosoma mansoni and Trichinella spiralis Derived-Antigens in Adjuvant Arthritis in Rats: Role of FOXP3+ Treg Cells.Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice.Contractile, but not endothelial, dysfunction in early inflammatory arthritis: a possible role for matrix metalloproteinase-9The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic DiseasesNon-MHC risk alleles in rheumatoid arthritis and in the syntenic chromosome regions of corresponding animal models.LEAPS therapeutic vaccines as antigen specific suppressors of inflammation in infectious and autoimmune diseases.Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells.Rheumatoid arthritis vaccine therapies: perspectives and lessons from therapeutic ligand epitope antigen presentation system vaccines for models of rheumatoid arthritisCo-stimulatory and Co-inhibitory Pathways in Autoimmunity.ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis modelEfficient and Non-Toxic Biological Response Carrier Delivering TNF-α shRNA for Gene Silencing in a Murine Model of Rheumatoid Arthritis.Periploca forrestii Saponin Ameliorates Murine CFA-Induced Arthritis by Suppressing Cytokine Production.Adjuvant-Induced Arthritis in Guinea Pigs.Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis.Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritisImmunoselected STRO-3+ mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritisThe inflammatory role of phagocyte apoptotic pathways in rheumatic diseases.BF02, a recombinant TNFR2 fusion protein, alleviates adjuvant arthritis by regulating T lymphocytes in rats.
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Evaluation of therapeutic targets in animal models of arthritis: how does it relate to rheumatoid arthritis?
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on August 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Evaluation of therapeutic targ ...... elate to rheumatoid arthritis?
@en
Evaluation of therapeutic targ ...... elate to rheumatoid arthritis?
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type
label
Evaluation of therapeutic targ ...... elate to rheumatoid arthritis?
@en
Evaluation of therapeutic targ ...... elate to rheumatoid arthritis?
@nl
prefLabel
Evaluation of therapeutic targ ...... elate to rheumatoid arthritis?
@en
Evaluation of therapeutic targ ...... elate to rheumatoid arthritis?
@nl
P2093
P2860
P356
P1476
Evaluation of therapeutic targ ...... elate to rheumatoid arthritis?
@en
P2093
Lisette Bevaart
Margriet J Vervoordeldonk
Paul P Tak
P2860
P304
P356
10.1002/ART.27503
P577
2010-08-01T00:00:00Z