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The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsmicroRNA-181a is involved in insulin-like growth factor-1-mediated regulation of the transcription factor CREB1Liver-derived IGF-I regulates mean life span in miceInsulin-like growth factor binding proteins: a structural perspective.Physical activity, inflammation, and volume of the aging brainAlterations in function and expression of ABC transporters at blood-brain barrier under diabetes and the clinical significances.Antagonism of brain insulin-like growth factor-1 receptors blocks estradiol effects on memory and levels of hippocampal synaptic proteins in ovariectomized ratsWheel running attenuates microglia proliferation and increases expression of a proneurogenic phenotype in the hippocampus of aged mice.Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons.Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1Brain metabolic dysfunction at the core of Alzheimer's disease.Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline.Neurobiological markers of exercise-related brain plasticity in older adults.Beneficial effects of novel antagonists of GHRH in different models of Alzheimer's diseaseSomatotropic signaling: trade-offs between growth, reproductive development, and longevityRelationships between diabetes and cognitive impairmentCrosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging.Insulin-like Signaling Promotes Glial Phagocytic Clearance of Degenerating Axons through Regulation of Draper.Sirtuins and Their Roles in Brain Aging and Neurodegenerative DisordersOpening up the DNA methylome of dementiaInsulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease.Beta-amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease.Generating new neurons to circumvent your fears: the role of IGF signaling.Cell biology of normal brain aging: synaptic plasticity-cell death.MicroRNA-98 induces an Alzheimer's disease-like disturbance by targeting insulin-like growth factor 1.Combined administration of cerebrolysin and donepezil induces plastic changes in prefrontal cortex in aged mice.Insulin-like growth factor-1 and insulin-like growth factor binding protein 3 and risk of postoperative cognitive dysfunction.Glial contributions to neuronal health and disease: new insights from Drosophila.A Putative Mechanism of Age-Related Synaptic Dysfunction Based on the Impact of IGF-1 Receptor Signaling on Synaptic CaMKIIα Phosphorylation.Analysis of Association of Genetic Markers in the LUZP2 and FBXO40 Genes with the Normal Variability in Cognitive Performance in the Elderly.The Therapeutic Potential of Metformin in Neurodegenerative Diseases
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 September 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
IGF-I and the aging mammalian brain.
@en
IGF-I and the aging mammalian brain.
@nl
type
label
IGF-I and the aging mammalian brain.
@en
IGF-I and the aging mammalian brain.
@nl
prefLabel
IGF-I and the aging mammalian brain.
@en
IGF-I and the aging mammalian brain.
@nl
P1476
IGF-I and the aging mammalian brain
@en
P2093
P356
10.1016/J.EXGER.2010.08.022
P577
2010-09-21T00:00:00Z