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A Concerted Action Of Estradiol And Insulin Like Growth Factor I Underlies Sex Differences In Mood Regulation By Exercise.Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice.Oral administration of a GSK3 inhibitor increases brain insulin-like growth factor I levelsRole of insulin-like growth factor I signaling in neurodegenerative diseases.Role of serum insulin-like growth factor I in mammalian brain aging.Learning of the conditioned eye-blink response is impaired by an antisense insulin-like growth factor I oligonucleotideIGF-1 in autosomal dominant cerebellar ataxia - open-label trial.Acute exercise does not modify brain activity and memory performance in APP/PS1 mice.Long-term depression of glutamate-induced gamma-aminobutyric acid release in cerebellum by insulin-like growth factor IEmerging roles of insulin-like growth factor-I in the adult brain.Circulating insulin-like growth factor I and cognitive function: neuromodulation throughout the lifespan.IGF-I and the aging mammalian brain.Astrocytes require insulin-like growth factor I to protect neurons against oxidative injury.Insulin-like growth factor I is an afferent trophic signal that modulates calbindin-28kD in adult Purkinje cells.Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation.A Coordinated Action of Blood-Borne and Brain Insulin-Like Growth Factor I in the Response to Traumatic Brain Injury.Exercise and cerebrovascular plasticity.Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-β-Induced Neuronal Death.A role for astrocytes in cerebellar deficits in frataxin deficiency: Protection by insulin-like growth factor I.A phosphatase-independent gain-of-function mutation in PTEN triggers aberrant cell growth in astrocytes through an autocrine IGF-1 loop.Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals.Astrocyte Resilience to Oxidative Stress Induced by Insulin-like Growth Factor I (IGF-I) Involves Preserved AKT (Protein Kinase B) Activity.Gonadal steroids as promoters of neuro-glial plasticity.Chronic intraventricular infusion of glial cell line-derived neurotrophic factor (GDNF) rescues some cerebellar Purkinje cells from heredodegeneration.Trophic effects of insulin-like growth factor-I on fetal rat hypothalamic cells in culture.Interaction of the signalling pathways of insulin-like growth factor-I and sex steroids in the neuroendocrine hypothalamus.Role of astroglia and insulin-like growth factor-I in gonadal hormone-dependent synaptic plasticity.Trophic effects of basic fibroblast growth factor on fetal rat hypothalamic cells: interactions with insulin-like growth factor I.IGF-1 in Friedreich's Ataxia - proof-of-concept trialExercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour.Reduced brain insulin-like growth factor I function during aging.A network of insulin peptides regulate glucose uptake by astrocytes: Potential new druggable targets for brain hypometabolism.Neuronal activity drives localized blood-brain-barrier transport of serum insulin-like growth factor-I into the CNS.Neuronal death by oxidative stress involves activation of FOXO3 through a two-arm pathway that activates stress kinases and attenuates insulin-like growth factor I signaling.Electrophoretic characterization of insulin growth factor (IGF-1) functionalized magnetic nanoparticles.Insulin-like growth factor I modifies electrophysiological properties of rat brain stem neurons.Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signaling.Growth promoting effects of IGF-I on fetal hypothalamic cell lines under serum-free culture conditions.Highly efficient and specific gene transfer to Purkinje cells in vivo using a herpes simplex virus I amplicon.Independent alterations in the central and peripheral somatosensory pathways in rat diabetic neuropathy.
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description
onderzoeker
@nl
researcher, ORCID: 0000-0001-8107-7947
@en
name
Ignacio Torres Aleman
@ast
Ignacio Torres Aleman
@en
Ignacio Torres Aleman
@es
Ignacio Torres Aleman
@nl
Ignacio Torres Aleman
@sl
type
label
Ignacio Torres Aleman
@ast
Ignacio Torres Aleman
@en
Ignacio Torres Aleman
@es
Ignacio Torres Aleman
@nl
Ignacio Torres Aleman
@sl
altLabel
Torres-Aleman I
@en
prefLabel
Ignacio Torres Aleman
@ast
Ignacio Torres Aleman
@en
Ignacio Torres Aleman
@es
Ignacio Torres Aleman
@nl
Ignacio Torres Aleman
@sl
P106
P108
P1153
51261628300
P21
P31
P496
0000-0001-8107-7947