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High affinity binding sites for the Wilms' tumour suppressor protein WT1How aneuploidy affects metabolic control and causes cancerDown-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatmentChromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1Genetic instability of cancer cells is proportional to their degree of aneuploidyGrowth-inhibitory activity and downregulation of the class II tumor-suppressor gene H-rev107 in tumor cell lines and experimental tumorsGenome-wide detection of allelic imbalance using human SNPs and high-density DNA arrays.Impaired FHIT expression characterizes serous ovarian carcinomaAneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation but is found to support aneuploidy.The cellular and molecular basis of prostate cancer.Single nucleotide polymorphisms associated with colorectal cancer susceptibility and loss of heterozygosity in a Taiwanese population.Mycoplasmas and oncogenesis: persistent infection and multistage malignant transformation.A new functional classification of tumor-suppressing genes and its therapeutic implications.Structural analysis of the GAP-related domain from neurofibromin and its implicationsAuto-catalysed progression of aneuploidy explains the Hayflick limit of cultured cells, carcinogen-induced tumours in mice, and the age distribution of human cancerSegregation of recombinant chromatids following mitotic crossing over in yeastReplication timing aberrations and aneuploidy in peripheral blood lymphocytes of breast cancer patients.Correlation of individual papilloma latency time with DNA adducts, 8-hydroxy-2'-deoxyguanosine, and the rate of DNA synthesis in the epidermis of mice treated with 7,12-dimethylbenz[alpha]anthraceneCancer genesKrox20/EGR2 deficiency accelerates cell growth and differentiation in the monocytic lineage and decreases bone massProtonation preferentially stabilizes minor tautomers of the halouracils: IRMPD action spectroscopy and theoretical studies.Mechanisms underlying losses of heterozygosity in human colorectal cancersProgression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer.Induced chromosomal exchange directs the segregation of recombinant chromatids in mitosis of DrosophilaFunctional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3.Abnormal chromosome repair and risk of developing cancer.Avian erythroblastosis virus E26: only one (myb) of two cell-derived coding regions is necessary for oncogenicityOncogenes and tumor suppressor genes: new biochemical tests.Genome-wide search for loss of heterozygosity in transgenic mouse tumors reveals candidate tumor suppressor genes on chromosomes 9 and 16.Identification of the MN antigen as a diagnostic biomarker of cervical intraepithelial squamous and glandular neoplasia and cervical carcinomas.Identification of a cell-surface glycoprotein associated with normal mammary and extramammary epithelial cells.Prognostic implications of p53 protein, epidermal growth factor receptor, and Ki-67 labelling in brain tumoursIncreased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells.Skin-specific expression of a truncated E1a oncoprotein binding to p105-Rb leads to abnormal hair follicle maturation without increased epidermal proliferation.Transcription factor AP-1 activity is required for initiation of DNA synthesis and is lost during cellular aging.Altered chromosome 6 in immortal human fibroblastsAneuploidy correlated 100% with chemical transformation of Chinese hamster cells.Unmutated proto-src coding region is tumorigenic if expressed from the promoter of Rous sarcoma virus: implications for the gene-mutation hypothesis of cancer.Host range restrictions of oncogenes: myc genes transform avian but not mammalian cells and mht/raf genes transform mammalian but not avian cells.Toxicological and pathological applications of proliferating cell nuclear antigen (PCNA), a novel endogenous marker for cell proliferation.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Human tumor suppressor genes.
@en
Human tumor suppressor genes.
@nl
type
label
Human tumor suppressor genes.
@en
Human tumor suppressor genes.
@nl
prefLabel
Human tumor suppressor genes.
@en
Human tumor suppressor genes.
@nl
P1476
Human tumor suppressor genes.
@en
P2093
Stanbridge EJ
P304
P356
10.1146/ANNUREV.GE.24.120190.003151
P577
1990-01-01T00:00:00Z