APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.
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APC(CDH1) targets MgcRacGAP for destruction in the late M phasemiR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cellsCdc20: a potential novel therapeutic target for cancer treatmentAPC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.Meiotic control of the APC/C: similarities & differences from mitosis.Transforming growth factor β1 increases p27 levels via synthesis and degradation mechanisms in the hyperproliferative gastric epithelium in rats.Targeting Cdc20 as a novel cancer therapeutic strategy.Insights into phosphorylation-dependent mechanisms regulating USP1 protein stability during the cell cycle.Changing the ubiquitin landscape during viral manipulation of the DNA damage response.Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity.DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway.The APC/C Ubiquitin Ligase: From Cell Biology to TumorigenesisMechanistic insights into aging, cell-cycle progression, and stress response.APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing.Regulation of APC/C-Cdh1 and its function in neuronal survivalCdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent mannerActivation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress.APC/CCDC20 and APC/C play pivotal roles in the process of embryonic development in Artemia sinica.The anaphase promoting complex regulates yeast lifespan and rDNA stability by targeting Fob1 for degradationSelenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells.PTEN loss in the continuum of common cancers, rare syndromes and mouse models.The emerging role of APC/CCdh1 in development.Genetic alterations of PTEN in human melanoma.Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation.REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1.Transcriptome analysis of neoplastic hemocytes in soft-shell clams Mya arenaria: Focus on cell cycle molecular mechanismCdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.PMA induces SnoN proteolysis and CD61 expression through an autocrine mechanism.Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7.Suppressor of cytokine signaling 1 blocks mitosis in human melanoma cells.New Functions of APC/C Ubiquitin Ligase in the Nervous System and Its Role in Alzheimer's Disease.NEK7 is required for G1 progression and procentriole formation.Antagonistic Gcn5-Hda1 interactions revealed by mutations to the Anaphase Promoting Complex in yeastThe mito::mKate2 mouse: A far-red fluorescent reporter mouse line for tracking mitochondrial dynamics in vivo.Cytokinesis arrest and multiple centrosomes in B cell chronic lymphocytic leukaemia.The role of APC/C(Cdh1) in replication stress and origin of genomic instability.The impact of Mir-9 regulation in normal and malignant hematopoiesis.
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APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 11 October 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.
@en
APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.
@nl
type
label
APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.
@en
APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.
@nl
prefLabel
APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.
@en
APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.
@nl
P2093
P2860
P356
P1433
P1476
APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.
@en
P2093
Takeo Fujita
Xinxian Qiao
P2860
P304
P356
10.4161/CC.9.19.13585
P577
2010-10-11T00:00:00Z