Chemotherapy against human African trypanosomiasis: is there a road to success?
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Virology, Epidemiology and Pathology of Glossina Hytrosavirus, and Its Control Prospects in Laboratory Colonies of the Tsetse Fly, Glossina pallidipes (Diptera; Glossinidae)Overview of the Diagnostic Methods Used in the Field for Human African Trypanosomiasis: What Could Change in the Next Years?Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasisChemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosomeSafety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasisExploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug designExamination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei.Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase.The anti-protozoan drug nifurtimox preferentially inhibits clonogenic tumor cells under hypoxic conditions.In vitro and in vivo evaluation of 28DAP010, a novel diamidine for treatment of second-stage African sleeping sicknessEmerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment.Cerebrospinal fluid neopterin as marker of the meningo-encephalitic stage of Trypanosoma brucei gambiense sleeping sickness.Evaluation of the diagnostic accuracy of prototype rapid tests for human African trypanosomiasis.Incorporating scale dependence in disease burden estimates: the case of human African trypanosomiasis in UgandaFrom health advice to taboo: community perspectives on the treatment of sleeping sickness in the Democratic Republic of Congo, a qualitative study.Trypanosoma brucei: inhibition of acetyl-CoA carboxylase by haloxyfopInduction of oxidative stress in Trypanosoma brucei by the antitrypanosomal dihydroquinoline OSU-40.Synthesis of novel amide and urea derivatives of thiazol-2-ethylamines and their activity against Trypanosoma brucei rhodesiense.Multiorgan dysfunction caused by travel-associated African trypanosomiasis.Screening North American plant extracts in vitro against Trypanosoma brucei for discovery of new antitrypanosomal drug leads.Evolution and Structural Analyses of Glossina morsitans (Diptera; Glossinidae) Tetraspanins.Identification of selective tubulin inhibitors as potential anti-trypanosomal agentsIn vitro and in vivo activities of 2-aminopyrazines and 2-aminopyridines in experimental models of human African trypanosomiasis.New biomarkers for stage determination in Trypanosoma brucei rhodesiense sleeping sickness patientsProduct feedback regulation implicated in translational control of the Trypanosoma brucei S-adenosylmethionine decarboxylase regulatory subunit prozymePharmacokinetics, Trypanosoma brucei gambiense efficacy, and time of drug action of DB829, a preclinical candidate for treatment of second-stage human African trypanosomiasisUrea Derivatives of 2-Aryl-benzothiazol-5-amines: A New Class of Potential Drugs for Human African Trypanosomiasis.Drug delivery systems in the treatment of African trypanosomiasis infections.Therapy of vector-borne protozoan infections in nonendemic settings.Human African trypanosomiasis in endemic populations and travellers.Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis.Proteomics: a new way to improve human African trypanosomiasis diagnosis?Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discoveryPopulation pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat.Inhibitors of Trypanosoma brucei trypanothione reductase: comparative molecular field analysis modeling and structural basis for selective inhibition.Stoking the drug target pipeline for human African trypanosomiasis.Suramin attenuates dystrophin-deficient cardiomyopathy in the mdx mouse model of duchenne muscular dystrophy.New insights in staging and chemotherapy of African trypanosomiasis and possible contribution of medicinal plants.A spatial genetics approach to inform vector control of tsetse flies (Glossina fuscipes fuscipes) in Northern Uganda.Monitoring the use of nifurtimox-eflornithine combination therapy (NECT) in the treatment of second stage gambiense human African trypanosomiasis
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Chemotherapy against human African trypanosomiasis: is there a road to success?
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 20 October 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Chemotherapy against human African trypanosomiasis: is there a road to success?
@en
Chemotherapy against human African trypanosomiasis: is there a road to success?
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type
label
Chemotherapy against human African trypanosomiasis: is there a road to success?
@en
Chemotherapy against human African trypanosomiasis: is there a road to success?
@nl
prefLabel
Chemotherapy against human African trypanosomiasis: is there a road to success?
@en
Chemotherapy against human African trypanosomiasis: is there a road to success?
@nl
P2860
P921
P1433
P1476
Chemotherapy against human African trypanosomiasis: is there a road to success?
@en
P2093
Christian Burri
P2860
P304
P356
10.1017/S0031182010001137
P577
2010-10-20T00:00:00Z