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NOTCH1 t(7;9)(NOTCH1:M1580_K2555) does not bind JAG1NOTCH1 HD domain mutants bind JAG1NOTCH1 PEST domain mutants bind JAG1NOTCH1 HD+PEST domain mutants bind JAG1JAG1:NOTCH1 HD domain mutantsJAG1:NOTCH1 HD domain mutant fragmentsJAG1:NOTCH1 PEST Domain MutantsDLL/JAGJAG1:NOTCH1 HD+PEST Domain MutantsJAG1:NOTCH1 HD+PEST Domain Mutant FragmentsJAG1:NOTCH1JAG1:NOTCH2JAG1 gene expression is inhibited by RUNX3NOTCH1 binds JAG1JAG1 binds NOTCH2JAG1:NOTCH3NOTCH3 binds JAG1JAG1:NOTCH4JAG1 binds NOTCH4
P527
P688
Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptorsA non-transmembrane form of Jagged-1 regulates the formation of matrix-dependent chord-like structuresPhysical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptorsThe notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cellsSoluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotypeMembers of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interactionJagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgammaThe CD46-Jagged1 interaction is critical for human TH1 immunityJagged1 (JAG1) mutations in patients with tetralogy of Fallot or pulmonic stenosisMutations in the human Jagged1 gene are responsible for Alagille syndromeAlagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural developmentIdentification and cloning of the human homolog (JAG1) of the rat Jagged1 gene from the Alagille syndrome critical region at 20p12Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cellsAn antisense oligonucleotide to the notch ligand jagged enhances fibroblast growth factor-induced angiogenesis in vitroFlexibility of the PDZ-binding motif in the micelle-bound form of Jagged-1 cytoplasmic tail
P921
Q37753038-1AC941BB-0C75-4116-85A7-9C242A4D96FBQ37753065-B7D10E09-3433-432F-AA36-8D0B390DF913Q37753098-7C326C87-6402-43C4-A010-AE58F5F70FD0Q37753199-E5684794-059F-464F-832C-97A502872B53Q50255973-2FBC027D-8FEF-430D-9D99-0C9488EF620FQ50255999-766C69E5-052A-408B-9515-84CAEF825900Q50256009-98AE51FC-9767-4DB3-96A2-F3069CA5523BQ50256016-07D14500-61EC-4699-BDBD-44DD50E9C260Q50256051-035D8AEA-78B1-4522-8B39-457D0C45FC0BQ50256064-0404463D-169E-4757-9A6E-F8AD744DEA6DQ50273288-693D11EE-8865-4C3B-A5C6-66612F92F806Q50273345-15B94365-F25B-42D7-B605-5D313B594809Q50290743-AE2FFBF4-AB47-4598-ADDF-D5656CAA1898Q50298622-BD15CAE8-5E72-480A-A377-B3FC27DCB8C7Q50298659-36B84880-9A89-4365-B325-6BCDEE41B64FQ55192469-8D7288FD-42D0-4498-898E-9BA5AEE9404FQ55219482-42750E02-61EE-4566-BE0F-733986075B64Q56856836-70C2BE38-972C-40B9-AEFF-84FAC7824E36Q56860726-66167D6D-364A-424B-8445-56B15345621C
P527
Q22010043-B26B28C1-5C7A-4A8C-9781-9BA8570FB29AQ22253207-88758F3E-08F1-42F6-B7FA-0D8E66A04BBFQ24290323-607D5305-FE3A-4423-8EE8-AA385BB32864Q24290490-A68560C7-4304-41CA-A838-BC58726670D5Q24291369-B1EF7CA8-BBFB-418A-A10B-EC9CD9EFF8A8Q24291667-76DE8F2F-38E8-4CF5-82D1-E5FFC23597B2Q24301127-F6DECE4D-C64F-4E71-B95A-7D635615A34BQ24301407-27E97791-2991-436E-907A-5BA29829E4C5Q24309460-5864E666-F658-4CA0-A15C-03668BBD6EE8Q24314702-3DE3B5A9-BB74-4AF8-817F-D7369818CD9FQ24314766-BEA060BC-804D-472A-BB4A-9E5DA927ECDBQ24321539-174C0C36-B8B4-49F8-A34C-2F6BBDB70DA6Q24328785-E6D986DA-04C2-45D5-93C3-DB8890013D00Q24329090-5558B03C-1FE9-451C-A37D-6A017C170F45Q24336333-99AC54D5-3B07-4A8D-BEDD-AD490059EFE5Q28910409-7EBE11AA-771D-45A9-AFD4-79CD65EFAB4B
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in JAG1
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
JAG1
@ca
JAG1
@es
JAG1
@nl
JAG1
@ru
Jagged canonical Notch ligand 1
@en
protéine jagged-1
@fr
type
label
JAG1
@ca
JAG1
@es
JAG1
@nl
JAG1
@ru
Jagged canonical Notch ligand 1
@en
protéine jagged-1
@fr
altLabel
AGS
@en
AHD
@en
AWS
@en
CD339
@en
CD339
@es
HJ1
@en
JAG 1
@ca
JAG-1
@ca
JAG1
@en
JAGL1
@en
prefLabel
JAG1
@ca
JAG1
@es
JAG1
@nl
JAG1
@ru
Jagged canonical Notch ligand 1
@en
protéine jagged-1
@fr
P527
P638
P680
P681
P682
P705
P352
P486
P637
P646
P31
P352
P486
D000072100
P527
P637
P638
P646
/m/02w1dg_
P680
P681
P682
P702
P703
P705
ENSP00000254958
ENSP00000481034
ENSP00000484139