The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.
about
Structure-Based Design of Covalent Siah InhibitorsTwo high-resolution structures of the human E3 ubiquitin ligase Siah1Mechanisms of synergism between antagonists of growth hormone-releasing hormone and antagonists of luteinizing hormone-releasing hormone in shrinking experimental benign prostatic hyperplasia.Recent progress in targeting cancer.Animal models relevant to human prostate carcinogenesis underlining the critical implication of prostatic stem/progenitor cells.The "Sharp" blade against HIF-mediated metastasis.Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6).ARF1 promotes prostate tumorigenesis via targeting oncogenic MAPK signaling.c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer.SIAH proteins: critical roles in leukemogenesis.Regulators and effectors of Siah ubiquitin ligases.Maintaining and reprogramming genomic androgen receptor activity in prostate cancer.Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.WWP2 ubiquitin ligase and its isoforms: new biological insight and promising disease targets.
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The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on September 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.
@en
The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.
@nl
type
label
The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.
@en
The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.
@nl
prefLabel
The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.
@en
The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.
@nl
P2093
P2860
P921
P356
P1433
P1476
The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.
@en
P2093
Jianfei Qi
Maurizio Pellecchia
Ze'ev A Ronai
P2860
P304
P356
10.18632/ONCOTARGET.171
P407
P5008
P577
2010-09-01T00:00:00Z