Isocitrate dehydrogenase mutations: a challenge to traditional views on the genesis and malignant progression of gliomas.
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IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in gliomaDiagnostic discrepancies in malignant astrocytoma due to limited small pathological tumor sample can be overcome by IDH1 testingAdvanced magnetic resonance imaging of the physical processes in human glioblastoma.Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgeryA miRNA signature for defining aggressive phenotype and prognosis in gliomas.IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resectionLOX expression and functional analysis in astrocytomas and impact of IDH1 mutationThe Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes.Subtyping of gliomas of various WHO grades by the application of immunohistochemistry.Role of isocitrate dehydrogenase in glioma.Tumor metabolism of malignant gliomas.MGMT testing--the challenges for biomarker-based glioma treatment.Impending Impact of Molecular Pathology on Classifying Adult Diffuse Gliomas.Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1.Stereotactic radiosurgery (SRS) in high-grade glioma: judicious selection of small target volumes improves results.Identification of MGMT promoter methylation sites correlating with gene expression and IDH1 mutation in gliomas.MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells.Genetic alterations of IDH1 and Vegf in brain tumors.IDH mutation analysis in gliomas as a diagnostic and prognostic biomarker.A phase I study of temozolomide and lapatinib combination in patients with recurrent high-grade gliomas.Neurocognitive function varies by IDH1 genetic mutation status in patients with malignant glioma prior to surgical resection.Clonal diversity in glioblastoma: is it clinically relevant?IDH1 mutations in diffusely infiltrating astrocytomas: grade specificity, association with protein expression, and clinical relevance.Utility of ATRX immunohistochemistry in diagnosis of adult diffuse gliomas.: Linking Metabolism and EpigeneticsBridging Cancer Biology with the Clinic: Comprehending and Exploiting IDH Gene Mutations in GliomasIdentification of a Prognostic Hypoxia-Associated Gene Set in IDH-Mutant Glioma
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P2860
Isocitrate dehydrogenase mutations: a challenge to traditional views on the genesis and malignant progression of gliomas.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 February 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Isocitrate dehydrogenase mutat ...... ignant progression of gliomas.
@en
Isocitrate dehydrogenase mutat ...... ignant progression of gliomas.
@nl
type
label
Isocitrate dehydrogenase mutat ...... ignant progression of gliomas.
@en
Isocitrate dehydrogenase mutat ...... ignant progression of gliomas.
@nl
prefLabel
Isocitrate dehydrogenase mutat ...... ignant progression of gliomas.
@en
Isocitrate dehydrogenase mutat ...... ignant progression of gliomas.
@nl
P2860
P50
P356
P1433
P1476
Isocitrate dehydrogenase mutat ...... ignant progression of gliomas.
@en
P2860
P304
P356
10.1002/GLIA.21130
P577
2011-02-03T00:00:00Z