Aberrantly activated anti-apoptotic signalling mechanisms in chronic lymphocytic leukaemia cells: clues to the identification of novel therapeutic targets.
about
Rewiring of sIgM-mediated intracellular signaling through the CD180 Toll-like receptor.Bruton's tyrosine kinase mediated signaling enhances leukemogenesis in a mouse model for chronic lymphocytic leukemia.The Bruton tyrosine kinase (BTK) inhibitor PCI-32765 synergistically increases proteasome inhibitor activity in diffuse large-B cell lymphoma (DLBCL) and mantle cell lymphoma (MCL) cells sensitive or resistant to bortezomib.Modulation of B-cell receptor and microenvironment signaling by a guanine exchange factor in B-cell malignanciesCD79B limits response of diffuse large B cell lymphoma to ibrutinib.Growth inhibition and apoptosis of neuroblastoma cells through ROS-independent MEK/ERK activation by sulforaphane.Heat shock protein-90 inhibitor, NVP-AUY922, is effective in combination with fludarabine against chronic lymphocytic leukemia cells cultured on CD40L-stromal layer and inhibits their activated/proliferative phenotype.Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes.The phosphoinositide 3-kinase pathway in chronic lymphocytic leukemia: evidence for phosphatase and tensin homolog deletion on chromosome 10 deregulation.Amplification of B cell receptor-Erk signaling by Rasgrf-1 overexpression in chronic lymphocytic leukemia.
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Aberrantly activated anti-apoptotic signalling mechanisms in chronic lymphocytic leukaemia cells: clues to the identification of novel therapeutic targets.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 April 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Aberrantly activated anti-apop ...... of novel therapeutic targets.
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Aberrantly activated anti-apop ...... of novel therapeutic targets.
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type
label
Aberrantly activated anti-apop ...... of novel therapeutic targets.
@en
Aberrantly activated anti-apop ...... of novel therapeutic targets.
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prefLabel
Aberrantly activated anti-apop ...... of novel therapeutic targets.
@en
Aberrantly activated anti-apop ...... of novel therapeutic targets.
@nl
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Aberrantly activated anti-apop ...... of novel therapeutic targets.
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Andrew J Steele
Archibald G Prentice
R Gitendra Wickremasinghe
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P304
P356
10.1111/J.1365-2141.2011.08676.X
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P577
2011-04-18T00:00:00Z