Synaptic defects in spinal muscular atrophy animal models.
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Neuromuscular Junctions as Key Contributors and Therapeutic Targets in Spinal Muscular AtrophyPresynaptic localization of Smn and hnRNP R in axon terminals of embryonic and postnatal mouse motoneuronsGenetic inhibition of JNK3 ameliorates spinal muscular atrophy.α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowthMutations in BICD2, which encodes a golgin and important motor adaptor, cause congenital autosomal-dominant spinal muscular atrophyThe Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA PhenotypeGain-of-function mutations in the ALS8 causative gene VAPB have detrimental effects on neurons and muscles.The role of laminins in the organization and function of neuromuscular junctions.Plastin 3 ameliorates spinal muscular atrophy via delayed axon pruning and improves neuromuscular junction functionality.Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy.Synaptotagmin-2, and -1, linked to neurotransmission impairment and vulnerability in Spinal Muscular Atrophy.Cytoskeletal changes in diseases of the nervous systemPharmacological c-Jun NH-Terminal Kinase (JNK) Pathway Inhibition Reduces Severity of Spinal Muscular Atrophy Disease in Mice
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Synaptic defects in spinal muscular atrophy animal models.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on January 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Synaptic defects in spinal muscular atrophy animal models.
@en
Synaptic defects in spinal muscular atrophy animal models.
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type
label
Synaptic defects in spinal muscular atrophy animal models.
@en
Synaptic defects in spinal muscular atrophy animal models.
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prefLabel
Synaptic defects in spinal muscular atrophy animal models.
@en
Synaptic defects in spinal muscular atrophy animal models.
@nl
P2860
P356
P1476
Synaptic defects in spinal muscular atrophy animal models.
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P2093
Laura Torres-Benito
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P304
P356
10.1002/DNEU.20912
P577
2012-01-01T00:00:00Z