To repress or not to repress: this is the guardian's question.
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The transcription factor p53: not a repressor, solely an activatorActivation of p53 transcriptional activity by SMRT: a histone deacetylase 3-independent function of a transcriptional corepressorGenome regulation by long noncoding RNAs.A Long Noncoding RNA Regulates Sister Chromatid CohesionHuman serum albumin and p53-activating peptide fusion protein is able to promote apoptosis and deliver fatty acid-modified moleculesMore targets, more pathways and more clues for mutant p53.p53 mutation status is a primary determinant of placenta-specific protein 1 expression in serous ovarian cancers.The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness.Mutant TP53 posttranslational modifications: challenges and opportunities.Uncovering the role of genomic "dark matter" in human disease.MicroRNA in teleost fish.ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.p53 binding to human genome: crowd control navigation in chromatin contextCharacterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions.GFI1 is repressed by p53 and inhibits DNA damage-induced apoptosis.AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere MaintenanceDistinct p53 genomic binding patterns in normal and cancer-derived human cells.A Temperature Sensitive Variant of p53 Drives p53-Dependent MicroRNA Expression without Evidence of Widespread Post-Transcriptional Gene Silencingp53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) AnalysesGene and protein analysis reveals that p53 pathway is functionally inactivated in cytogenetically normal Acute Myeloid Leukemia and Acute Promyelocytic LeukemiaNon-coding RNAs in Saccharomyces cerevisiae: what is the function?MicroRNAs in the p53 network: micromanagement of tumour suppression.Census and evaluation of p53 target genes.Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic.Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress.Identification of a p53-repressed gene module in breast cancer cells.Wild-type p53 binds to MYC promoter G-quadruplex.p53 Loses grip on PIK3CA expression leading to enhanced cell survival during platinum resistance.p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells.CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress.p53 can repress transcription of cell cycle genes through a p21(WAF1/CIP1)-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements.CDK1 interacts with iASPP to regulate colorectal cancer cell proliferation through p53 pathway.6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription.JHDM1B expression regulates ribosome biogenesis and cancer cell growth in a p53 dependent manner.
P2860
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P2860
To repress or not to repress: this is the guardian's question.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 19 May 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
@cs
name
To repress or not to repress: this is the guardian's question.
@en
To repress or not to repress: this is the guardian's question.
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To repress or not to repress: this is the guardian's question.
@en
To repress or not to repress: this is the guardian's question.
@nl
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To repress or not to repress: this is the guardian's question.
@en
To repress or not to repress: this is the guardian's question.
@nl
P1476
To repress or not to repress: this is the guardian's question.
@en
P304
P356
10.1016/J.TCB.2011.04.002
P577
2011-05-19T00:00:00Z