Towards systematic functional characterization of cancer genomes.
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Oncogenic Signaling Adaptor ProteinsRAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?Cancer Biology, Toxicology and Alternative Methods Development Go Hand-in-HandPacific biosciences sequencing technology for genotyping and variation discovery in human dataNon-synonymous variations in cancer and their effects on the human proteome: workflow for NGS data biocuration and proteome-wide analysis of TCGA data.Publisher’s Note:Abstraction for data integration:Fusing mammalian molecular, cellular and phenotype big datasets for better knowledge extraction.Abnormal promoter methylation of multiple tumor suppressor genes in human bronchial epithelial malignant cells.Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.Polygenic in vivo validation of cancer mutations using transposons.Integrative analysis of somatic mutations altering microRNA targeting in cancer genomes.Alteration of human blood cell transcriptome in uremia.Pathogenesis and prevention of hepatitis C virus-induced hepatocellular carcinoma.Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.Emerging insights into the molecular and cellular basis of glioblastoma.Identifying gnostic predictors of the vaccine response.MicroSCALE screening reveals genetic modifiers of therapeutic response in melanoma.Toward personalized cancer nanomedicine - past, present, and future.DINGO: differential network analysis in genomicsRSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer.Integration of cancer genomics with treatment selection: from the genome to predictive biomarkersDiscovery of small molecule cancer drugs: successes, challenges and opportunities.A methodological approach to unravel organ-specific breast cancer metastasis.Modeling and predicting clinical efficacy for drugs targeting the tumor milieu.Acetaldehyde and the genome: beyond nuclear DNA adducts and carcinogenesis.Detecting and targetting oncogenic fusion proteins in the genomic era.Precision medicine based on epigenomics: the paradigm of carcinoma of unknown primary.Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.ANKHD1 regulates cell cycle progression and proliferation in multiple myeloma cells.Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.The non-coding oncogene: a case of missing DNA evidence?Characterizing genomic alterations in cancer by complementary functional associations.Functional genomics to identify unforeseen cancer drug targets.Statistical Contributions to Bioinformatics: Design, Modeling, Structure Learning, and Integration.Synthetic Lethal Vulnerabilities in KRAS-Mutant Cancers.Functional Genomic Characterization of Cancer Genomes.Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping.CRISPR/Cas-based customization of pooled CRISPR libraries.Markers as mediators: A review and synthesis of epigenetics literaturePersonalized Integrated Network Modeling of the Cancer Proteome Atlas
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Towards systematic functional characterization of cancer genomes.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 17 June 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Towards systematic functional characterization of cancer genomes.
@en
Towards systematic functional characterization of cancer genomes.
@nl
type
label
Towards systematic functional characterization of cancer genomes.
@en
Towards systematic functional characterization of cancer genomes.
@nl
prefLabel
Towards systematic functional characterization of cancer genomes.
@en
Towards systematic functional characterization of cancer genomes.
@nl
P2860
P356
P1476
Towards systematic functional characterization of cancer genomes.
@en
P2093
Jesse S Boehm
William C Hahn
P2860
P2888
P304
P356
10.1038/NRG3013
P577
2011-06-17T00:00:00Z
P5875
P6179
1020190062