Hippocampal synaptic plasticity in Alzheimer's disease: what have we learned so far from transgenic models?
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Alzheimer mechanisms and therapeutic strategiesSynapses and Alzheimer's diseaseEmerging Link between Alzheimer's Disease and Homeostatic Synaptic PlasticityEarly synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptors.Stem cell therapy for Alzheimer's disease and related disorders: current status and future perspectivesPhysiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-βSynaptic deficits in layer 5 neurons precede overt structural decay in 5xFAD mice.Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer's disease.Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis.Multifaceted Roles of Metzincins in CNS Physiology and Pathology: From Synaptic Plasticity and Cognition to Neurodegenerative DisordersDegenerative alterations in noradrenergic neurons of the locus coeruleus in Alzheimer's diseaseGlobal analysis of S-nitrosylation sites in the wild type (APP) transgenic mouse brain-clues for synaptic pathology.Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus.Altered GluN2B NMDA receptor function and synaptic plasticity during early pathology in the PS2APP mouse model of Alzheimer's diseaseOpportunities and Limitations of Modelling Alzheimer's Disease with Induced Pluripotent Stem CellsDefective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease.Neuroprotective and neurotrophic actions of glucagon-like peptide-1: an emerging opportunity to treat neurodegenerative and cerebrovascular disordersSynaptic activity and Alzheimer's disease: a critical update.Computational modeling of the effects of amyloid-beta on release probability at hippocampal synapsesNeuropathological approaches to cerebral aging and neuroplasticity.Synaptic plasticity in multiple sclerosis and in experimental autoimmune encephalomyelitis.A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis.Combining two repurposed drugs as a promising approach for Alzheimer's disease therapyConsequences of inhibiting amyloid precursor protein processing enzymes on synaptic function and plasticity.Alzheimer's disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory.Targeting synaptic dysfunction in Alzheimer's disease therapy.The entorhinal cortex and neurotrophin signaling in Alzheimer's disease and other disorders.Brain-Derived Neurotrophic Factor in Alzheimer's Disease: Risk, Mechanisms, and Therapy.Synaptic activity protects against AD and FTD-like pathology via autophagic-lysosomal degradation.Emerging pathways driving early synaptic pathology in Alzheimer's disease.Bis(propyl)-cognitin Prevents β-amyloid-induced Memory Deficits as Well as Synaptic Formation and Plasticity Impairments via the Activation of PI3-K Pathway.Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein.Influence of cortical synaptic input on striatal neuronal dendritic arborization and sensitivity to excitotoxicity in corticostriatal coculture.Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission.Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease.Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.Firing properties of entorhinal cortex neurons and early alterations in an Alzheimer's disease transgenic model.Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity.Differences in Synaptic Dysfunction Between rTg4510 and APP/PS1 Mouse Models of Alzheimer's Disease.Age-dependent changes in hippocampal synaptic transmission and plasticity in the PLB1Triple Alzheimer mouse.
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Hippocampal synaptic plasticity in Alzheimer's disease: what have we learned so far from transgenic models?
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 July 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hippocampal synaptic plasticit ...... so far from transgenic models?
@en
Hippocampal synaptic plasticit ...... so far from transgenic models?
@nl
type
label
Hippocampal synaptic plasticit ...... so far from transgenic models?
@en
Hippocampal synaptic plasticit ...... so far from transgenic models?
@nl
prefLabel
Hippocampal synaptic plasticit ...... so far from transgenic models?
@en
Hippocampal synaptic plasticit ...... so far from transgenic models?
@nl
P2860
P356
P1476
Hippocampal synaptic plasticit ...... so far from transgenic models?
@en
P2093
Cristina Marchetti
P2860
P304
P356
10.1515/RNS.2011.035
P50
P577
2011-07-06T00:00:00Z