Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics. - Wikidata - awgldk - TriplyDB

Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics.

Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics.

http://www.wikidata.org/entity/Q37900558

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Rational and combinatorial tailoring of bioactive cyclic dipeptides Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity Targeting tumour proliferation with a small-molecule inhibitor of AICAR transformylase homodimerization Characterization of influenza vaccine immunogenicity using influenza antigen microarrays.Organic carbamates in drug design and medicinal chemistry Cone snail venomics: from novel biology to novel therapeutics.Library construction, selection and modification strategies to generate therapeutic peptide-based modulators of protein-protein interactions.Methods for the creation of cyclic Peptide libraries for use in lead discovery.5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists.Synthesis of constrained analogues of tryptophan.Intracellular Production of Cyclic Peptide Libraries with SICLOPPS.On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions.Targeting the bacteria-host interface: strategies in anti-adhesion therapy.Regulating toxin-antitoxin expression: controlled detonation of intracellular molecular timebombs Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects.Short peptides interfering with signaling pathways as new therapeutic tools for cancer treatment.The Potential Therapeutic Application of Peptides and Peptidomimetics in Cardiovascular Disease.Modern tools for the chemical ligation and synthesis of modified peptides and proteins.Design of a selenylsulfide-bridged EGFR dimerization arm mimic Linear aliphatic dialkynes as alternative linkers for double-click stapling of p53-derived peptides.Intramolecular Hydrogen Bonding Involving Organic Fluorine: NMR Investigations Corroborated by DFT-Based Theoretical Calculations.Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs.Modulation of Backbone Flexibility for Effective Dissociation of Antibacterial and Hemolytic Activity in Cyclic Peptides.Synthesis of nisin AB dicarba analogs using ring-closing metathesis: influence of sp(3) versus sp(2) hybridization of the α-carbon atom of residues dehydrobutyrine-2 and dehydroalanine-5 on the lipid II binding affinity.In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers.Synthesis of gem-diamino acid derivatives by a Hofmann rearrangement.Ester vs. amide on folding: a case study with a 2-residue synthetic peptide.1,2,3-Triazole Rings as a Disulfide Bond Mimetic in Chimeric AGRP-Melanocortin Peptides: Design, Synthesis, and Functional Characterization.Design, synthesis, and conformational analysis of 3-cyclo-butylcarbamoyl hydantoins as novel hydrogen bond driven universal peptidomimetics.Cyclodipeptides: An Overview of Their Biosynthesis and Biological Activity.Targeting cancer-specific glycans by cyclic peptide lectinomimics.Cyclopropane-Based Peptidomimetics Mimicking Wide-Ranging Secondary Structures of Peptides: Conformational Analysis and Their Use in Rational Ligand Optimization.C9/12 Ribbon-Like Structures in Hybrid Peptides Alternating α- and Thiazole-Based γ-Amino Acids.From Peptides to Peptidomimetics: A Strategy Based on the Structural Features of Cyclopropane.FT-IR and NMR structural markers for thiazole-based γ-peptide foldamers.Multifunctionalized sequence-defined oligomers from a single building block.Turning Peptide Sequences into Ribbon Foldamers by a Straightforward Multicyclization Reaction.Stabilization of the cysteine-rich conotoxin MrIA by using a 1,2,3-triazole as a disulfide bond mimetic.

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P2860

Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics.

http://www.wikidata.org/entity/Q37900558

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 12 July 2011

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics.

@en

Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics.

@nl

type

label

Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics.

@en

Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics.

@nl

prefLabel

Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics.

@en

Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics.

@nl

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Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics.

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Dirk T S Rijkers

http://www.w3.org/2001/XMLSchema#string

Johan Kemmink

http://www.w3.org/2001/XMLSchema#string

John A W Kruijtzer

http://www.w3.org/2001/XMLSchema#string

Rob M J Liskamp

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P2860

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.

Systematic analysis of helical protein interfaces reveals targets for synthetic inhibitors

All-atom model for stabilization of alpha-helical structure in peptides by hydrocarbon staples.

Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface

Structures of glycopeptide antibiotics with peptides that model bacterial cell-wall precursors

Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions.

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

A field guide to foldamers

P304

1626-1653

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scholarly article

P356

10.1002/CBIC.201000717

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11

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12

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2011-07-12T00:00:00Z

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21751324

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