Radiolabelled mass-balance excretion and metabolism studies in laboratory animals: are they still necessary?
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Identification of drug metabolites in human plasma or serum integrating metabolite prediction, LC-HRMS and untargeted data processing.HRMS: current usage, future directions and the promise of integration with unified data streams suited to post-acquisition mining.Assessment of potential drug interactions by characterization of human drug metabolism pathways using non-invasive bile sampling.Preclinical in vivo ADME studies in drug development: a critical review.The early estimation of circulating drug metabolites in humans.Radiolabeled mass-balance excretion and metabolism studies in laboratory animals: a commentary on why they are still necessary.Metabolite structure analysis by high-resolution MS: supporting drug-development studies.Dogs and monkeys in preclinical drug development: the challenge of reducing and replacing.The debate on animal ADME studies in drug development: an update.Introduction: use of radioactive compounds in drug discovery and development.Interspecies scaling of excretory amounts using allometry - retrospective analysis with rifapentine, aztreonam, carumonam, pefloxacin, miloxacin, trovafloxacin, doripenem, imipenem, cefozopran, ceftazidime, linezolid for urinary excretion and rifapeConference report: a hitchhiker's guide to outsourcing ADME studies: the inside of outsourcing.Selected scientific topics of the 11th International Isotope Symposium on the Synthesis and Applications of Isotopes and Isotopically Labeled Compounds.
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P2860
Radiolabelled mass-balance excretion and metabolism studies in laboratory animals: are they still necessary?
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artículo científico
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Radiolabelled mass-balance exc ...... als: are they still necessary?
@en
Radiolabelled mass-balance exc ...... als: are they still necessary?
@nl
type
label
Radiolabelled mass-balance exc ...... als: are they still necessary?
@en
Radiolabelled mass-balance exc ...... als: are they still necessary?
@nl
prefLabel
Radiolabelled mass-balance exc ...... als: are they still necessary?
@en
Radiolabelled mass-balance exc ...... als: are they still necessary?
@nl
P2093
P2860
P1433
P1476
Radiolabelled mass-balance exc ...... als: are they still necessary?
@en
P2093
Angus N Nedderman
Dennis A Smith
R Scott Obach
P2860
P356
10.3109/00498254.2011.621985
P407
P577
2011-10-12T00:00:00Z