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Regulation of PP2A by Sphingolipid Metabolism and SignalingAblation of dihydroceramide desaturase confers resistance to etoposide-induced apoptosis in vitroSphingosine-1-Phosphate Metabolism and Its Role in the Development of Inflammatory Bowel DiseaseS1pping fire: Sphingosine-1-phosphate signaling as an emerging target in inflammatory bowel disease and colitis-associated cancerSphingosine kinase 1 mediates head & neck squamous cell carcinoma invasion through sphingosine 1-phosphate receptor 1.Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma.Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activityChemical interrogation of the neuronal kinome using a primary cell-based screening assay.Regulation of ceramide synthase by casein kinase 2-dependent phosphorylation in Saccharomyces cerevisiaeDisruption of sphingolipid metabolism augments ceramide-induced autophagy in preeclampsia.Polarity switching mass spectrometry imaging of healthy and cancerous hen ovarian tissue sections by infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI)The janus face of lipids in human breast cancer: how polyunsaturated Fatty acids affect tumor cell hallmarks.Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITIONLiver acid sphingomyelinase inhibits growth of metastatic colon cancer.Sphingosine-1-phosphate in inflammatory bowel disease and colitis-associated colon cancer: the fat's in the firePlasma sphingolipids and lung cancer: a population-based, nested case-control study.Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progressionSphingolipids in colon cancer.Carbohydrate-containing molecules as potential biomarkers in colon cancer.The role of sphingolipids in drug metabolism and transport.Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis.The emerging role of acid sphingomyelinase in autophagy.Microbubble-based enhancement of radiation effect: Role of cell membrane ceramide metabolism.Obesity and melanoma: could fat be fueling malignancy?Disease monitoring of hepatocellular carcinoma through metabolomics.Delivery systems of ceramide in targeted cancer therapy: ceramide alone or in combination with other anti-tumor agents.Solenopsin A and analogs exhibit ceramide-like biological activity.Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism.Chemistry and Biology of HPAs: A Family of Ceramide Trafficking Inhibitors.Fragment-Based Hologram QSAR Studies on a Series of 2,4-Dioxopyrimidine-1-Carboxamides As Highly Potent Inhibitors of Acid CeramidaseAltered sphingolipid metabolism in patients with metastatic pancreatic cancer.MiR-124 acts as a tumor suppressor by inhibiting the expression of sphingosine kinase 1 and its downstream signaling in head and neck squamous cell carcinoma.Simultaneous Quantification of Sphingolipids in Small Quantities of Liver by LC-MS/MS.Predictive value of sphingosine kinase 1 expression in neoadjuvant treatment of breast cancer.Kefir: a powerful probiotics with anticancer properties.TGF-β/SMAD3 Pathway Stimulates Sphingosine-1 Phosphate Receptor 3 Expression: IMPLICATION OF SPHINGOSINE-1 PHOSPHATE RECEPTOR 3 IN LUNG ADENOCARCINOMA PROGRESSION.Autocrine/paracrine sphingosine-1-phosphate fuels proliferative and stemness qualities of glioblastoma stem cells.Identification of novel CERT ligands as potential ceramide trafficking inhibitors.Genetic deletion of sphingosine kinase 1 suppresses mouse breast tumor development in an HER2 transgenic model.The combination of a sphingosine kinase 2 inhibitor (ABC294640) and a Bcl-2 inhibitor (ABT-199) displays synergistic anti-myeloma effects in myeloma cells without a t(11;14) translocation.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Sphingolipids in cancer.
@en
Sphingolipids in cancer.
@nl
type
label
Sphingolipids in cancer.
@en
Sphingolipids in cancer.
@nl
prefLabel
Sphingolipids in cancer.
@en
Sphingolipids in cancer.
@nl
P2093
P1476
Sphingolipids in cancer.
@en
P2093
Hideki Furuya
Toshihiko Kawamori
Yoshiko Shimizu
P2888
P304
P356
10.1007/S10555-011-9304-1
P577
2011-12-01T00:00:00Z