It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.
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Post-translational modifications as key regulators of TNF-induced necroptosisMolecular crosstalk between apoptosis, necroptosis, and survival signalingConverging roles of caspases in inflammasome activation, cell death and innate immunityProgrammed necrosis in acute kidney injuryCaspase-8 as a regulator of tumor cell motilityRole of mitochondria in apoptotic and necroptotic cell death in the developing brainDie another way--non-apoptotic mechanisms of cell deathComprehensive genomic characterization of head and neck squamous cell carcinomasThe role of sex differences in autophagy in the heart during coxsackievirus B3-induced myocarditisNovel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP proteinSurvival function of the FADD-CASPASE-8-cFLIP(L) complexKey roles of necroptotic factors in promoting tumor growthCaspase 8 polymorphisms contribute to the prognosis of advanced lung adenocarcinoma patients after platinum-based chemotherapy.MicroRNA-296-5p Promotes Invasiveness through Downregulation of Nerve Growth Factor Receptor and Caspase-8.Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activationNecroptosisBeyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory diseaseNuclear expression of β-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells.Caspase functions in cell death and disease.TAK1 control of cell death.Regulated cell death in AKI.Combination effects of SMAC mimetic birinapant with TNFα, TRAIL, and docetaxel in preclinical models of HNSCC.RIP1 Cleavage in the Kinase Domain Regulates TRAIL-Induced NF-κB Activation and Lymphoma Survival.Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell DeathThe molluscum contagiosum virus death effector domain containing protein MC160 RxDL motifs are not required for its known viral immune evasion functions.Integrated analysis of oral tongue squamous cell carcinoma identifies key variants and pathways linked to risk habits, HPV, clinical parameters and tumor recurrence.Autoimmunity: twenty years in the Fas laneTwo independent pathways of regulated necrosis mediate ischemia-reperfusion injuryTargeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network.The RIP1-kinase inhibitor necrostatin-1 prevents osmotic nephrosis and contrast-induced AKI in mice.Apoptosis and necrosis in the liverCaspase-8 inhibition represses initial human monocyte activation in septic shock model.TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation.FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium.Programmed cell death in Parkinson's diseaseDAMPs and autophagy: cellular adaptation to injury and unscheduled cell death.Caspase-8 and FLIP regulate RIG-I/MDA5-induced innate immune host responses to picornaviruses.Necroptosis in immunity and ischemia-reperfusion injury.
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It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.
@en
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.
@nl
type
label
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.
@en
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.
@nl
prefLabel
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.
@en
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.
@nl
P2860
P356
P1476
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.
@en
P2093
Andrew Oberst
P2860
P2888
P304
P356
10.1038/NRM3214
P577
2011-10-21T00:00:00Z