It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival. - Wikidata - awgldk - TriplyDB

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

http://www.wikidata.org/entity/Q37947994

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Post-translational modifications as key regulators of TNF-induced necroptosis Molecular crosstalk between apoptosis, necroptosis, and survival signaling Converging roles of caspases in inflammasome activation, cell death and innate immunity Programmed necrosis in acute kidney injury Caspase-8 as a regulator of tumor cell motility Role of mitochondria in apoptotic and necroptotic cell death in the developing brain Die another way--non-apoptotic mechanisms of cell death Comprehensive genomic characterization of head and neck squamous cell carcinomas The role of sex differences in autophagy in the heart during coxsackievirus B3-induced myocarditis Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein Survival function of the FADD-CASPASE-8-cFLIP(L) complex Key roles of necroptotic factors in promoting tumor growth Caspase 8 polymorphisms contribute to the prognosis of advanced lung adenocarcinoma patients after platinum-based chemotherapy.MicroRNA-296-5p Promotes Invasiveness through Downregulation of Nerve Growth Factor Receptor and Caspase-8.Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation Necroptosis Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease Nuclear expression of β-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells.Caspase functions in cell death and disease.TAK1 control of cell death.Regulated cell death in AKI.Combination effects of SMAC mimetic birinapant with TNFα, TRAIL, and docetaxel in preclinical models of HNSCC.RIP1 Cleavage in the Kinase Domain Regulates TRAIL-Induced NF-κB Activation and Lymphoma Survival.Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death The molluscum contagiosum virus death effector domain containing protein MC160 RxDL motifs are not required for its known viral immune evasion functions.Integrated analysis of oral tongue squamous cell carcinoma identifies key variants and pathways linked to risk habits, HPV, clinical parameters and tumor recurrence.Autoimmunity: twenty years in the Fas lane Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network.The RIP1-kinase inhibitor necrostatin-1 prevents osmotic nephrosis and contrast-induced AKI in mice.Apoptosis and necrosis in the liver Caspase-8 inhibition represses initial human monocyte activation in septic shock model.TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation.FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium.Programmed cell death in Parkinson's disease DAMPs and autophagy: cellular adaptation to injury and unscheduled cell death.Caspase-8 and FLIP regulate RIG-I/MDA5-induced innate immune host responses to picornaviruses.Necroptosis in immunity and ischemia-reperfusion injury.

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It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

http://www.wikidata.org/entity/Q37947994

description

article científic

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article scientifique

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artigo científico

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artikel ilmiah

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name

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

@en

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

@nl

type

label

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

@en

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

@nl

prefLabel

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

@en

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

@nl

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P1433

Nature Reviews Molecular Cell Biology

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It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival.

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Andrew Oberst

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P2860

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

Linear ubiquitination prevents inflammation and regulates immune signalling

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

TNF-alpha induces two distinct caspase-8 activation pathways

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

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757-763

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scholarly article

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10.1038/NRM3214

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11

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12

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Douglas R. Green

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2011-10-21T00:00:00Z

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51732778

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22016059

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