Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2. - Wikidata - awgldk - TriplyDB

Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

http://www.wikidata.org/entity/Q37955769

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TIGAR is required for efficient intestinal regeneration and tumorigenesis Metabolic Effects of Known and Novel HDAC and SIRT Inhibitors in Glioblastomas Independently or Combined with Temozolomide Alanine and aspartate aminotransferase and glutamine-cycling pathway: their roles in pathogenesis of metabolic syndrome.Targeting cancer metabolism.Malignant behaviorial characteristics of CD133(+/-) glioblastoma cells from a Northern Chinese population Extracellular RNA mediates and marks cancer progression.Chemosensitivity of IDH1-Mutated Gliomas Due to an Impairment in PARP1-Mediated DNA Repair.Pediatric Gliomatosis Cerebri: A Review of 15 Years.Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma.Isocitrate dehydrogenase 2 inhibits gastric cancer cell invasion via matrix metalloproteinase 7.Glutamate and α-ketoglutarate: key players in glioma metabolism.Expression of R132H mutational IDH1 in human U87 glioblastoma cells affects the SREBP1a pathway and induces cellular proliferation.High IDH1 expression is associated with a poor prognosis in cytogenetically normal acute myeloid leukemia.Parallel evolution of IDH2 gene in cetaceans, primates and bats.Metabolic alterations due to IDH1 mutation in glioma: opening for therapeutic opportunities?Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI).

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Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

http://www.wikidata.org/entity/Q37955769

description

article científic

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article scientifique

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articol științific

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articolo scientifico

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artigo científico

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artigo científico

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artigo científico

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artikel ilmiah

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artículo científico

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name

Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

@en

Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

@nl

type

label

Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

@en

Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

@nl

prefLabel

Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

@en

Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

@nl

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Current Opinion in Oncology

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Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.

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Alexandra Borodovsky

http://www.w3.org/2001/XMLSchema#string

Gregory J Riggins

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Meghan J Seltzer

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P2860

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Mutations in the D-2-hydroxyglutarate dehydrogenase gene cause D-2-hydroxyglutaric aciduria.

Understanding the Warburg effect: the metabolic requirements of cell proliferation

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

Recurring mutations found by sequencing an acute myeloid leukemia genome

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells

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83-89

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scholarly article

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10.1097/CCO.0B013E32834D816A

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1

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24

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2012-01-01T00:00:00Z

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22080945

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4612588

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