Cross-functional E3 ligases Parkin and C-terminus Hsp70-interacting protein in neurodegenerative disorders.
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Dysregulation of glutathione homeostasis in neurodegenerative diseasesThe Beta-amyloid protein of Alzheimer's disease: communication breakdown by modifying the neuronal cytoskeletonA Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?Legal but lethal: functional protein aggregation at the verge of toxicityAtaxia, dementia, and hypogonadotropism caused by disordered ubiquitinationAtaxia and hypogonadism caused by the loss of ubiquitin ligase activity of the U box protein CHIPSIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system.Trehalose improves human fibroblast deficits in a new CHIP-mutation related ataxia.Linking aβ42-induced hyperexcitability to neurodegeneration, learning and motor deficits, and a shorter lifespan in an Alzheimer's modelRevealing Missing Human Protein Isoforms Based on Ab Initio Prediction, RNA-seq and ProteomicsQuantitative Proteomics of Human Fibroblasts with I1061T Mutation in Niemann-Pick C1 (NPC1) Protein Provides Insights into the Disease Pathogenesis.Enhancement of ubiquitin conjugation activity reduces intracellular aggregation of V76D mutant γD-crystallin.Phosphorylation of CHIP at Ser20 by Cdk5 promotes tAIF-mediated neuronal death.Cancer stem-like cell related protein CD166 degrades through E3 ubiquitin ligase CHIP in head and neck cancer.Mechanisms underlying synaptic vulnerability and degeneration in neurodegenerative disease.Alterations in the E3 ligases Parkin and CHIP result in unique metabolic signaling defects and mitochondrial quality control issues.Ubiquitin Ligases and Posttranslational Regulation of Energy in the Heart: The Hand that Feeds.Repair or destruction-an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasisNH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease.TDP-43 loss of cellular function through aggregation requires additional structural determinants beyond its C-terminal Q/N prion-like domainChaperone-Mediated Regulation of Choline Acetyltransferase Protein Stability and Activity by HSC/HSP70, HSP90, and p97/VCP.Post-translational modification of OCT4 in breast cancer tumorigenesis.
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P2860
Cross-functional E3 ligases Parkin and C-terminus Hsp70-interacting protein in neurodegenerative disorders.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artículo científico
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name
Cross-functional E3 ligases Pa ...... n neurodegenerative disorders.
@en
Cross-functional E3 ligases Pa ...... n neurodegenerative disorders.
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type
label
Cross-functional E3 ligases Pa ...... n neurodegenerative disorders.
@en
Cross-functional E3 ligases Pa ...... n neurodegenerative disorders.
@nl
prefLabel
Cross-functional E3 ligases Pa ...... n neurodegenerative disorders.
@en
Cross-functional E3 ligases Pa ...... n neurodegenerative disorders.
@nl
P2093
P2860
P1476
Cross-functional E3 ligases Pa ...... in neurodegenerative disorders
@en
P2093
Henry W Querfurth
Kaveri Pradhan
Rashmi K Ambasta
P2860
P304
P356
10.1111/J.1471-4159.2011.07588.X
P407
P50
P577
2011-12-21T00:00:00Z