Metabolic network modeling and simulation for drug targeting and discovery.
about
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewRapid countermeasure discovery against Francisella tularensis based on a metabolic network reconstructionLeveraging systems biology approaches in clinical pharmacologyMetabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental AnalysisFrom in vitro to in vivo Models of Bacterial Biofilm-Related Infections.Prediction of metabolic flux distribution from gene expression data based on the flux minimization principle.CLASH: Complementary Linkage with Anchoring and Scoring for Heterogeneous biomolecular and clinical dataRETRACTED: Predicting new molecular targets for rhein using network pharmacology.Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.In silico methods for drug repurposing and pharmacologyFunctional genomics of Plasmodium falciparum using metabolic modelling and analysisGenome-scale metabolic model in guiding metabolic engineering of microbial improvement.Network pharmacology strategies toward multi-target anticancer therapies: from computational models to experimental design principles.A conceptual review on systems biology in health and diseases: from biological networks to modern therapeutics.Metabolic engineering with systems biology tools to optimize production of prokaryotic secondary metabolites.Genome-scale reconstruction of the metabolic network in Pseudomonas stutzeri A1501.RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations.In silico metabolic engineering of Bacillus subtilis for improved production of riboflavin, Egl-237, (R,R)-2,3-butanediol and isobutanol.Biological function through network topology: a survey of the human diseasome.Flux-coupled genes and their use in metabolic flux analysis.Network Pharmacology Strategies Toward Multi-Target Anticancer Therapies: From Computational Models to Experimental Design Principles.Framework and resource for more than 11,000 gene-transcript-protein-reaction associations in human metabolism.A systems approach to traditional oriental medicine.Proliferation inhibition of cisplatin-resistant ovarian cancer cells using drugs screened by integrating a metabolic model and transcriptomic data.Machine Learning Methods for Analysis of Metabolic Data and Metabolic Pathway Modeling.A kidney-specific genome-scale metabolic network model for analyzing focal segmental glomerulosclerosis.Modeling the differences in biochemical capabilities of pseudomonas species by flux balance analysis: how good are genome-scale metabolic networks at predicting the differences?Editorial: Michael Shuler's legacy in biochemical engineering.
P2860
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P2860
Metabolic network modeling and simulation for drug targeting and discovery.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Metabolic network modeling and simulation for drug targeting and discovery.
@en
Metabolic network modeling and simulation for drug targeting and discovery.
@nl
type
label
Metabolic network modeling and simulation for drug targeting and discovery.
@en
Metabolic network modeling and simulation for drug targeting and discovery.
@nl
prefLabel
Metabolic network modeling and simulation for drug targeting and discovery.
@en
Metabolic network modeling and simulation for drug targeting and discovery.
@nl
P2860
P356
P1476
Metabolic network modeling and simulation for drug targeting and discovery.
@en
P2093
Seung Bum Sohn
P2860
P304
P356
10.1002/BIOT.201100159
P577
2011-11-29T00:00:00Z