T-cell acute lymphoblastic leukaemia: recent molecular biology findings.
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Current Strategies for the Detection of Minimal Residual Disease in Childhood Acute Lymphoblastic LeukemiaDiagnosis and subclassification of acute lymphoblastic leukemiaLow PKCα expression within the MRD-HR stratum defines a new subgroup of childhood T-ALL with very poor outcome.Deep sequencing and SNP array analyses of pediatric T-cell acute lymphoblastic leukemia reveal NOTCH1 mutations in minor subclones and a high incidence of uniparental isodisomies affecting CDKN2AHarnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: eliminating activity by targeting at different levelsImproving outcomes in childhood T-cell acute lymphoblastic leukemia: promising results from the Children's Oncology Group incorporating nelarabine into front-line therapy.The evolution of malignant and reactive γδ + T cell clones in a relapse T-ALL case after allogeneic stem cell transplantation.MicroRNA-100/99a, deregulated in acute lymphoblastic leukaemia, suppress proliferation and promote apoptosis by regulating the FKBP51 and IGF1R/mTOR signalling pathwaysAntileukemic Scalarane Sesterterpenoids and Meroditerpenoid from Carteriospongia (Phyllospongia) sp., Induce Apoptosis via Dual Inhibitory Effects on Topoisomerase II and Hsp90.The TCR γδ repertoire and relative gene expression characteristics of T-ALL cases with biclonal malignant Vδ1 and Vδ2 T cells.Dnmt3a haploinsufficiency cooperates with oncogenic Kras to promote an early-onset T-cell acute lymphoblastic leukemia.Epigenetic regulation of cell signaling pathways in acute lymphoblastic leukemia.Genomic characterization of acute leukemias.Peripheral T-cell and NK cell lymphoproliferative disorders: cell of origin, clinical and pathological implications.Gamma secretase inhibitors enhance vincristine-induced apoptosis in T-ALL in a NOTCH-independent manner.Different outcome of T cell acute lymphoblastic leukemia with translocation t(11;14) treated in two consecutive children leukemia group EORTC trials.Highly aggressive T-cell acute lymphoblastic leukemia with t(8;14)(q24;q11): extensive genetic characterization and achievement of early molecular remission and long-term survival in an adult patient.Placing ion channels into a signaling network of T cells: from maturing thymocytes to healthy T lymphocytes or leukemic T lymphoblasts.A Novel Cryptic Three-Way Translocation t(2;9;18)(p23.2;p21.3;q21.33) with Deletion of Tumor Suppressor Genes in 9p21.3 and 13q14 in a T-Cell Acute Lymphoblastic Leukemia.PI3K/mTOR inhibition upregulates NOTCH-MYC signalling leading to an impaired cytotoxic response.Distinctive disease subgroups according to differentiation stages in adult patients with T-cell acute lymphoblastic leukemia.Gene mutation profiles and prognostic implications in Korean patients with T-lymphoblastic leukemia.Elevated TRIB2 with NOTCH1 activation in paediatric/adult T-ALL.
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P2860
T-cell acute lymphoblastic leukaemia: recent molecular biology findings.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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T-cell acute lymphoblastic leukaemia: recent molecular biology findings.
@en
T-cell acute lymphoblastic leukaemia: recent molecular biology findings.
@nl
type
label
T-cell acute lymphoblastic leukaemia: recent molecular biology findings.
@en
T-cell acute lymphoblastic leukaemia: recent molecular biology findings.
@nl
prefLabel
T-cell acute lymphoblastic leukaemia: recent molecular biology findings.
@en
T-cell acute lymphoblastic leukaemia: recent molecular biology findings.
@nl
P2860
P50
P1476
T-cell acute lymphoblastic leukaemia: recent molecular biology findings.
@en
P2093
Małgorzata Dawidowska
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P304
P356
10.1111/J.1365-2141.2011.08957.X
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P577
2011-12-07T00:00:00Z