Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
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Non-canonical signaling mode of the epidermal growth factor receptor familyDefining the blanks--pharmacochaperoning of SLC6 transporters and ABC transportersInhibitors of Protein Translocation Across the ER MembraneAn ER complex of ODR-4 and ODR-8/Ufm1 specific protease 2 promotes GPCR maturation by a Ufm1-independent mechanismStructure of the Sec61 channel opened by a signal sequenceHow Polyomaviruses Exploit the ERAD Machinery to Cause InfectionStructure of the TatC core of the twin-arginine protein transport systemStructural model for the protein-translocating element of the twin-arginine transport systemThe Glove-like Structure of the Conserved Membrane Protein TatC Provides Insight into Signal Sequence Recognition in Twin-Arginine TranslocationStructure of the SecY channel during initiation of protein translocationStructure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å ResolutionStructures of the Sec61 complex engaged in nascent peptide translocation or membrane insertionVisualization of a polytopic membrane protein during SecY-mediated membrane insertionKey steps in ERAD of luminal ER proteins reconstituted with purified componentsThe yeast ERAD-C ubiquitin ligase Doa10 recognizes an intramembrane degronAutoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD.A bacterial toxin and a nonenveloped virus hijack ER-to-cytosol membrane translocation pathways to cause diseaseSignal peptide-binding drug as a selective inhibitor of co-translational protein translocationThe biological functions of Naa10 - From amino-terminal acetylation to human diseaseNew insights into the mechanism of chloroplast protein import and its integration with protein quality control, organelle biogenesis and development.Lateral gates: β-barrels get in on the act.Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations.Molecular basis of the dominant negative effect of a glycine transporter 2 mutation associated with hyperekplexia.Two alternative binding mechanisms connect the protein translocation Sec71-Sec72 complex with heat shock proteins.Live cell imaging shows reversible assembly of the TatA component of the twin-arginine protein transport system.The knottin-like Blufensin family regulates genes involved in nuclear import and the secretory pathway in barley-powdery mildew interactions.Variation in the ribosome interacting loop of the Sec61α from Giardia lambliaHsp90 modulates PPARγ activity in a mouse model of nonalcoholic fatty liver disease.Dynamic interaction of the sec translocon with the chaperone PpiDSpontaneous transmembrane helix insertion thermodynamically mimics translocon-guided insertion.dPob/EMC is essential for biosynthesis of rhodopsin and other multi-pass membrane proteins in Drosophila photoreceptors.Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells.SecA drives transmembrane insertion of RodZ, an unusual single-span membrane protein.The bacterial flagellar protein export apparatus processively transports flagellar proteins even with extremely infrequent ATP hydrolysis.The code for directing proteins for translocation across ER membrane: SRP cotranslationally recognizes specific features of a signal sequence.The interplay of Hrd3 and the molecular chaperone system ensures efficient degradation of malfolded secretory proteins.The Get1/2 transmembrane complex is an endoplasmic-reticulum membrane protein insertase.Cotranslational folding inhibits translocation from within the ribosome-Sec61 translocon complex.Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon.Cotranslational stabilization of Sec62/63 within the ER Sec61 translocon is controlled by distinct substrate-driven translocation events.
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P2860
Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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name
Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
@en
Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
@nl
type
label
Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
@en
Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
@nl
prefLabel
Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
@en
Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
@nl
P1476
Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
@en
P2093
Eunyong Park
P356
10.1146/ANNUREV-BIOPHYS-050511-102312
P50
P577
2011-12-16T00:00:00Z