Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon.
about
Inhibitors of Protein Translocation Across the ER MembraneStructure of the Sec61 channel opened by a signal sequenceTernatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex.A comprehensive assessment of RNA-seq protocols for degraded and low-quantity samplesMycolactone subverts immunity by selectively blocking the Sec61 translocon.Natural products as probes in pharmaceutical research.A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA).Mycolactone reveals the substrate-driven complexity of Sec61-dependent transmembrane protein biogenesis.Mechanistic insights into the inhibition of Sec61-dependent co- and post-translational translocation by mycolactone.Inhibitors of protein translocation across membranes of the secretory pathway: novel antimicrobial and anticancer agents.Driving Forces of Translocation Through Bacterial Translocon SecYEG.Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4.
P2860
Q27021065-8E86C64D-F45E-4DC4-9604-C5DA737D9A42Q27330079-E48C6197-9C74-4274-9B9D-49F035B28D26Q30388201-007C5248-2A53-4BE5-892A-7F48D57641EFQ36393221-0A9BE63D-35CC-4D0E-BEC4-79B67524DE09Q37500335-53C48121-85B2-4165-9C04-F1E9731C10C5Q38599715-BCCDED5F-F5E5-4B8D-8578-326D5EBBC4DEQ38725180-0A5279D9-C33D-481D-9B91-AFD9C29D63B9Q38951193-B9B0FF2B-9D66-4BBB-91E7-28E17B7BD6EFQ40794641-E13C796D-1CBF-4BAA-A05C-6DB1672CC0DEQ47228430-3270FF84-18C1-4062-8270-834D15C397CFQ47734450-8DDDC72A-0B1C-4723-B456-5B2177960985Q53702000-EB0EECB7-F4C4-4D1F-A2ED-FC12CA2FACAD
P2860
Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Decatransin, a new natural pro ...... t the Sec61/SecYEG translocon.
@ast
Decatransin, a new natural pro ...... t the Sec61/SecYEG translocon.
@en
type
label
Decatransin, a new natural pro ...... t the Sec61/SecYEG translocon.
@ast
Decatransin, a new natural pro ...... t the Sec61/SecYEG translocon.
@en
prefLabel
Decatransin, a new natural pro ...... t the Sec61/SecYEG translocon.
@ast
Decatransin, a new natural pro ...... t the Sec61/SecYEG translocon.
@en
P2093
P2860
P356
P1476
Decatransin, a new natural pro ...... t the Sec61/SecYEG translocon.
@en
P2093
Benedikt W Bauer
Bhupinder Bhullar
Britta Knapp
Christian Studer
David Estoppey
Dominic Hoepfner
Edward J Oakeley
Frank Petersen
Guglielmo Roma
Joanne Wong
P2860
P304
P356
10.1242/JCS.165746
P407
P577
2015-01-22T00:00:00Z