Role and Therapeutic Potential of the Pro-Longevity Factor FOXO and Its Regulators in Neurodegenerative Disease.

Role and Therapeutic Potential of the Pro-Longevity Factor FOXO and Its Regulators in Neurodegenerative Disease.

Item
http://www.wikidata.org/entity/Q37987917
Redox regulation of FoxO transcription factorsThe Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicityInsulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neuronsForkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop.Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's DiseaseReduced Insulin/Insulin-Like Growth Factor Receptor Signaling Mitigates Defective Dendrite Morphogenesis in Mutants of the ER Stress Sensor IRE-1.AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease.Pathways to decoding the clinical potential of stress response FOXO-interaction networks for Huntington's disease: of gene prioritization and context dependence.Regulatory Role of Redox Balance in Determination of Neural Precursor Cell Fate.The role of the PI3K-Akt signaling pathway in the developmental competence of bovine oocytes.FOXOs modulate proteasome activity in human-induced pluripotent stem cells of Huntington's disease and their derived neural cells.
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Role and Therapeutic Potential of the Pro-Longevity Factor FOXO and Its Regulators in Neurodegenerative Disease.

Item
http://www.wikidata.org/entity/Q37987917
description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artículo científico
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name
Role and Therapeutic Potential ...... in Neurodegenerative Disease.
@en
Role and Therapeutic Potential ...... in Neurodegenerative Disease.
@nl
type
label
Role and Therapeutic Potential ...... in Neurodegenerative Disease.
@en
Role and Therapeutic Potential ...... in Neurodegenerative Disease.
@nl
prefLabel
Role and Therapeutic Potential ...... in Neurodegenerative Disease.
@en
Role and Therapeutic Potential ...... in Neurodegenerative Disease.
@nl
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P2093
P2860
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P31
P356
P478
P50
P577
P5875
P698
P921
P932
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P1433
P1476
Role and Therapeutic Potential ...... s in Neurodegenerative Disease
@en
P2093
P2860
P304
P31
P356
P478
P50
P577
P5875
P698
P921
P932