An evolutionary view of the mechanism for immune and genome diversity.
about
The lethal toxin from Australian funnel-web spiders is encoded by an intronless geneRepair of oxidative DNA damage and cancer: recent progress in DNA base excision repairαβ TCR-mediated recognition: relevance to tumor-antigen discovery and cancer immunotherapyReshaping Antibody DiversityGeneration and repair of AID-initiated DNA lesions in B lymphocytes.A novel mouse model for the hyper-IgM syndrome: a spontaneous activation-induced cytidine deaminase mutation leading to complete loss of Ig class switching and reduced somatic hypermutationAPE1 is dispensable for S-region cleavage but required for its repair in class switch recombination.Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime.Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminaseFostering of advanced mutualism with gut microbiota by Immunoglobulin A.Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3' regulatory region.Interplay between Target Sequences and Repair Pathways Determines Distinct Outcomes of AID-Initiated LesionsFunctional requirements of AID's higher order structures and their interaction with RNA-binding proteinsMechanisms of epigenetic deregulation in lymphoid neoplasms.The origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity.Induction of activation-induced cytidine deaminase-targeting adaptor 14-3-3γ is mediated by NF-κB-dependent recruitment of CFP1 to the 5'-CpG-3'-rich 14-3-3γ promoter and is sustained by E2A.Antigenic variation and transmission fitness as drivers of bacterial strain structure.Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instabilityControl of Transposon-Mediated Directed Mutation by the Escherichia coli Phosphoenolpyruvate:Sugar Phosphotransferase System.RNA binding to APOBEC deaminases; Not simply a substrate for C to U editing.The Top1 paradox: Friend and foe of the eukaryotic genome.Chromatin and transcriptional tango on the immune dance floor.B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.Single nucleotide editing without DNA cleavage using CRISPR/Cas9-deaminase in the sea urchin embryo.An evolutionary perspective on the systems of adaptive immunity.The interplay between G-quadruplex and Transcription.
P2860
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P2860
An evolutionary view of the mechanism for immune and genome diversity.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
An evolutionary view of the mechanism for immune and genome diversity.
@en
type
label
An evolutionary view of the mechanism for immune and genome diversity.
@en
prefLabel
An evolutionary view of the mechanism for immune and genome diversity.
@en
P2093
P356
P1476
An evolutionary view of the mechanism for immune and genome diversity.
@en
P2093
Andre Stanlie
Lucia Kato
Maki Kobayashi
Masatoshi Aida
Nasim A Begum
P304
P356
10.4049/JIMMUNOL.1102397
P407
P50
P577
2012-04-01T00:00:00Z