HTS techniques for patch clamp-based ion channel screening - advances and economy. - Wikidata - awgldk - TriplyDB

HTS techniques for patch clamp-based ion channel screening - advances and economy.

HTS techniques for patch clamp-based ion channel screening - advances and economy.

http://www.wikidata.org/entity/Q38002949

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Genetically-encoded tools for cAMP probing and modulation in living systems Automated parallel recordings of topologically identified single ion channels Single-molecule bioelectronics.Schizophrenia-Associated hERG channel Kv11.1-3.1 Exhibits a Unique Trafficking Deficit that is Rescued Through Proteasome Inhibition for High Throughput Screening Automated Electrophysiological and Pharmacological Evaluation of Human Pluripotent Stem Cell-Derived Cardiomyocytes.Diverse Applications of Nanomedicine.Predicting drug-induced QT prolongation and torsades de pointes: a review of preclinical endpoint measures.Cardiotoxicity screening: a review of rapid-throughput in vitro approaches.Identification of State-Dependent Blockers for Voltage-Gated Calcium Channels Using a FLIPR-Based Assay.Human iPSC-Derived Cardiomyocytes for Investigation of Disease Mechanisms and Therapeutic Strategies in Inherited Arrhythmia Syndromes: Strengths and Limitations.Ion channel recordings on an injection-molded polymer chip.Droplet-based lipid bilayer system integrated with microfluidic channels for solution exchange.NaV Channels: Assaying Biosynthesis, Trafficking, Function.Design and Implementation of High-Throughput Screening Assays.Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

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HTS techniques for patch clamp-based ion channel screening - advances and economy.

http://www.wikidata.org/entity/Q38002949

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HTS techniques for patch clamp-based ion channel screening - advances and economy.

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HTS techniques for patch clamp-based ion channel screening - advances and economy.

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HTS techniques for patch clamp-based ion channel screening - advances and economy.

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17460441.2012.682056

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Expert Opinion on Drug Discovery

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HTS techniques for patch clamp-based ion channel screening - advances and economy.

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Cecilia Farre

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Niels Fertig

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P2860

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans

How many drug targets are there?

TRP channels as cellular sensors

Population patch clamp improves data consistency and success rates in the measurement of ionic currents.

Whole cell patch clamp recording performed on a planar glass chip

Cell-based assays and instrumentation for screening ion-channel targets.

High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology.

Drug-induced torsades de pointes and implications for drug development.

State-of-the-Art Automated Patch Clamp Devices: Heat Activation, Action Potentials, and High Throughput in Ion Channel Screening.

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515-524

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scholarly article

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10.1517/17460441.2012.682056

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6

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2012-04-16T00:00:00Z

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22507077

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