Population patch clamp improves data consistency and success rates in the measurement of ionic currents.
about
High throughput screening technologies for ion channelsVariability in high-throughput ion-channel screening data and consequences for cardiac safety assessment.Profiling diverse compounds by flux- and electrophysiology-based primary screens for inhibition of human Ether-à-go-go related gene potassium channels.Validation and optimization of novel high-throughput assays for human epithelial sodium channels.Automated High-Throughput Characterization of Single Neurons by Means of Simplified Spiking Models.Comparison of cell expression formats for the characterization of GABA(A) channels using a microfluidic patch clamp system.A new electro-optical approach for conductance measurement: an assay for the study of drugs acting on ligand-gated ion channels.The hERG potassium channel as a therapeutic target.New cell models and assays in cardiac safety profiling.Microtechnologies for membrane protein studiesHigh Throughput Techniques for Discovering New Glycine Receptor Modulators and their Binding Sites.Ion channels as novel therapeutic targets in the treatment of pain.Screening technologies for ion channel drug discovery.Keeping the rhythm: hERG and beyond in cardiovascular safety pharmacology.HTS techniques for patch clamp-based ion channel screening - advances and economy.Physical and virtual screening methods for marine toxins and drug discovery targeting nicotinic acetylcholine receptors.Pharmacological and electrophysiological characterization of AZSMO-23, an activator of the hERG K(+) channel.Transforming TRP channel drug discovery using medium-throughput electrophysiological assays.Automated electrophysiology makes the pace for cardiac ion channel safety screening.Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia.Novel methodology to identify TRPV1 antagonists independent of capsaicin activation.Ion channel electrophysiology via integrated planar patch-clamp chip with on-demand drug exchange.Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia.Early identification of hERG liability in drug discovery programs by automated patch clamp.Two approaches for addressing electrochemical electrode arrays with reduced external connections.Overview of Electrophysiological Techniques.Validation of a high-throughput, automated electrophysiology platform for the screening of nicotinic agonists and antagonists.Automated Patch Clamp Analysis of nAChα7 and Na(V)1.7 Channels.CRACking ion channel targets: 2nd annual Ion Channel Targets Conference. 12-13 September 2006, Boston, MA, USA.A High-Throughput Electrophysiology Assay Identifies Inhibitors of the Inwardly Rectifying Potassium Channel Kir7.1.Renaissance of ion channel research and drug discovery by patch clamp automation.Novel 384-well population patch clamp electrophysiology assays for Ca2+-activated K+ channels.
P2860
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P2860
Population patch clamp improves data consistency and success rates in the measurement of ionic currents.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Population patch clamp improve ...... measurement of ionic currents.
@ast
Population patch clamp improve ...... measurement of ionic currents.
@en
type
label
Population patch clamp improve ...... measurement of ionic currents.
@ast
Population patch clamp improve ...... measurement of ionic currents.
@en
prefLabel
Population patch clamp improve ...... measurement of ionic currents.
@ast
Population patch clamp improve ...... measurement of ionic currents.
@en
P2093
P356
P1476
Population patch clamp improve ...... measurement of ionic currents.
@en
P2093
Alan Finkel
Andrew Wittel
James Costantin
Jan Hughes
Naibo Yang
Shawn Handran
P304
P356
10.1177/1087057106288050
P577
2006-06-07T00:00:00Z