Regulation and cellular functions of class II phosphoinositide 3-kinases.
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Targeting p110gamma in gastrointestinal cancers: attack on multiple frontsClass III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane trafficPhosphoinositides: tiny lipids with giant impact on cell regulationArf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism.The therapeutic potential of targeting the PI3K pathway in pediatric brain tumorsSignaling by the phosphoinositide 3-kinase family in immune cellsRegulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesisSequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis.Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway.PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium functionClass II phosphoinositide 3-kinases contribute to endothelial cells morphogenesis.Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation.PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting.Involvement of class II phosphoinositide 3-kinase α-isoform in antigen-induced degranulation in RBL-2H3 cells.Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasisPlentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012).Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and SensitivityEssential role of class II phosphatidylinositol-3-kinase-C2α in sphingosine 1-phosphate receptor-1-mediated signaling and migration in endothelial cellsThe role of lipids in the control of autophagyPhosphatidylinositol 3-phosphates-at the interface between cell signalling and membrane traffic.Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice.Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression.3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer.High-Throughput Small Interfering RNA Screening Identifies Phosphatidylinositol 3-Kinase Class II Alpha as Important for Production of Human Cytomegalovirus VirionsOrganizing polarized delivery of exosomes at synapsesClasses of phosphoinositide 3-kinases at a glance.Using FRET to analyse signals controlling cell adhesion and migration.Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling.Phosphoinositide 3-kinases as accelerators and brakes of autophagy.PI3K/AKT signaling pathway and cancer: an updated review.New insight into the intracellular roles of class II phosphoinositide 3-kinases.Role of phosphoinositide 3-kinase in the pathogenesis of acute pancreatitis.Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMOGene of the month: PIK3CA.Phosphoinositide 3-Kinase-Dependent Signalling Pathways in Cutaneous Squamous Cell Carcinomas.Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.Novel roles for class II Phosphoinositide 3-Kinase C2β in signalling pathways involved in prostate cancer cell invasion.PI3K Signaling in Tissue Hyper-Proliferation: From Overgrowth Syndromes to Kidney Cysts.PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signallingPhosphatidlyinositol-3-kinase C2 beta (PI3KC2β) is a potential new target to treat IgE mediated disease
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P2860
Regulation and cellular functions of class II phosphoinositide 3-kinases.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Regulation and cellular functions of class II phosphoinositide 3-kinases.
@en
type
label
Regulation and cellular functions of class II phosphoinositide 3-kinases.
@en
prefLabel
Regulation and cellular functions of class II phosphoinositide 3-kinases.
@en
P356
P1433
P1476
Regulation and cellular functions of class II phosphoinositide 3-kinases
@en
P2093
Tania Maffucci
P304
P356
10.1042/BJ20120008
P407
P577
2012-05-01T00:00:00Z