Chromosomal instability and aneuploidy in cancer: from yeast to man
about
Unbalanced replication as a major source of genetic instability in cancer cellsGenomic Changes in Normal Breast Tissue in Women at Normal Risk or at High Risk for Breast CancerRibosomal proteins as unrevealed caretakers for cellular stress and genomic instabilityDNA damage associated with mitosis and cytokinesis failureQuantitative assessment of chromosome instability induced through chemical disruption of mitotic progressionRe-replication of a centromere induces chromosomal instability and aneuploidyReduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutationPlasticity of the Leishmania genome leading to gene copy number variations and drug resistanceA System to Study Aneuploidy In VivoSterile inflammation in DrosophilaTranscriptional control of mitosis: deregulation and cancerSystems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence"The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer.Loss of centrioles causes chromosomal instability in vertebrate somatic cells.Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival.The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell-cell adhesionIncreased microtubule assembly rates influence chromosomal instability in colorectal cancer cells.Modulation of phosphatidylinositol 4-phosphate levels by CaBP7 controls cytokinesis in mammalian cellsDeregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathwayAurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interactionSex-determination system in the diploid yeast Zygosaccharomyces sapaeIncreased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan.The motor protein KIF14 inhibits tumor growth and cancer metastasis in lung adenocarcinomaTranscriptional consequence and impaired gametogenesis with high-grade aneuploidy in Arabidopsis thalianaGlobal changes in gene expression associated with phenotypic switching of wild yeastCyclin B2 and p53 control proper timing of centrosome separationMitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast.High-throughput analysis of yeast replicative aging using a microfluidic systemAn assay to detect in vivo Y chromosome loss in Drosophila wing disc cells.Truncation of POC1A associated with short stature and extreme insulin resistanceADHD-associated dopamine transporter, latrophilin and neurofibromin share a dopamine-related locomotor signature in DrosophilaAneuploidy in health, disease, and aging.Cyclins and cell cycle control in cancer and disease.Reducing signs of aging and increasing lifespan by drug synergy.Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivoO-linked N-acetylglucosamine cycling regulates mitotic spindle organization.Multi-layered cancer chromosomal instability phenotype.Long-term cultured mesenchymal stem cells frequently develop genomic mutations but do not undergo malignant transformation.The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification.Chromosomal instability, aneuploidy and routine high-resolution DNA content analysis in oral cancer risk evaluation.
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Chromosomal instability and aneuploidy in cancer: from yeast to man
description
article científic
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article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Chromosomal instability and aneuploidy in cancer: from yeast to man
@en
type
label
Chromosomal instability and aneuploidy in cancer: from yeast to man
@en
prefLabel
Chromosomal instability and aneuploidy in cancer: from yeast to man
@en
P2860
P356
P1433
P1476
Chromosomal instability and aneuploidy in cancer: from yeast to man
@en
P2093
Sarah J Pfau
P2860
P304
P356
10.1038/EMBOR.2012.65
P577
2012-06-01T00:00:00Z