Keap1: one stone kills three birds Nrf2, IKKβ and Bcl-2/Bcl-xL.
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Update on the Kelch-like (KLHL) gene familyROS and ROS-Mediated Cellular SignalingThe role of the ubiquitin proteasome system in cerebellar development and medulloblastomaRNAi Screen for NRF2 Inducers Identifies Targets That Rescue Primary Lung Epithelial Cells from Cigarette Smoke Induced Radical StressOvercoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924Keap1 modulates the redox cycle and hepatocyte cell cycle in regenerating liver.Insight into the intermolecular recognition mechanism between Keap1 and IKKβ combining homology modelling, protein-protein docking, molecular dynamics simulations and virtual alanine mutationProtopanaxtriol protects against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington's diseaseCancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405.Ovotoxicants 4-vinylcyclohexene 1,2-monoepoxide and 4-vinylcyclohexene diepoxide disrupt redox status and modify different electrophile sensitive target enzymes and genes in Drosophila melanogasterAntioxidant response genes sequence variants and BPD susceptibility in VLBW infants.The pineal gland: A model for adrenergic modulation of ubiquitin ligasesAberrant Keap1 methylation in breast cancer and association with clinicopathological features.Glycoproteomics using fluid-based specimens in the discovery of lung cancer protein biomarkers: promise and challenge.NADPH oxidase 4 deficiency increases tubular cell death during acute ischemic reperfusion injury.Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma.The Nrf2 pathway in the progression of renal disease.The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update.Activation of proteinase-activated receptor 2 prevents apoptosis of lung cancer cells.The 'N-factors' in pancreatic cancer: functional relevance of NF-κB, NFAT and Nrf2 in pancreatic cancer.Keap1/Nrf2 impairing revised: are we missing the single nucleotide polymorphisms?Binding of disordered proteins to a protein hub.Apigenin in cancer therapy: anti-cancer effects and mechanisms of action.Beneficial Role of Some Natural Products to Attenuate the Diabetic Cardiomyopathy Through Nrf2 Pathway in Cell Culture and Animal Models.Oxidative Stress and Metabolism: The NF-Erythroid 2 p45-Related Factor 2:Kelch-like ECH-Associated Protein 1 System and Regulatory T Lymphocytes in Ischemic AKI.Carboxyethylgermanium sesquioxide (Ge-132) treatment during in vitro culture protects fertilized porcine embryos against oxidative stress induced apoptosis.Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2).Activated Nrf2 impairs liver regeneration in mice by activation of genes involved in cell-cycle control and apoptosis.Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription.Lycopene acts through inhibition of IκB kinase to suppress NF-κB signaling in human prostate and breast cancer cells.Epigenetic versus Genetic Deregulation of the KEAP1/NRF2 Axis in Solid Tumors: Focus on Methylation and Noncoding RNAs.Antioxidant and antiproliferative activities of methanolic extract from a neglected agricultural product: corn cobs.
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Keap1: one stone kills three birds Nrf2, IKKβ and Bcl-2/Bcl-xL.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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Keap1: one stone kills three birds Nrf2, IKKβ and Bcl-2/Bcl-xL.
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Keap1: one stone kills three birds Nrf2, IKKβ and Bcl-2/Bcl-xL.
@en
prefLabel
Keap1: one stone kills three birds Nrf2, IKKβ and Bcl-2/Bcl-xL.
@en
P2093
P1433
P1476
Keap1: one stone kills three birds Nrf2, IKKβ and Bcl-2/Bcl-xL.
@en
P2093
Baofu Zhang
DongSheng Pei
FeiFei Chen
Guan Jiang
HuiZhong Li
JunNian Zheng
LianTao Li
P356
10.1016/J.CANLET.2012.06.007
P407
P577
2012-06-26T00:00:00Z