Metabolic regulation by SIRT3: implications for tumorigenesis.
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Physiological consequences of complex II inhibition for aging, disease, and the mKATP channelStructures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanismSirtuins and nonalcoholic fatty liver diseaseNuclear DNA damage signalling to mitochondria in ageingGeldanamycin-induced osteosarcoma cell death is associated with hyperacetylation and loss of mitochondrial pool of heat shock protein 60 (hsp60)Sirtuins: guardians of mammalian healthspan.Emerging role of sirtuins on tumorigenesis: possible link between aging and cancerSirT3 regulates the mitochondrial unfolded protein response.Profilin-1 suppresses tumorigenicity in pancreatic cancer through regulation of the SIRT3-HIF1α axis.SIRT3 & SIRT7: Potential Novel Biomarkers for Determining Outcome in Pancreatic Cancer Patients.Metabolic Regulation by Lysine Malonylation, Succinylation, and Glutarylation.When Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow?Sirtuins Function as the Modulators in Aging-related Diseases in Common or RespectivelyPro-Proliferative Function of Mitochondrial Sirtuin Deacetylase SIRT3 in Human MelanomaOverexpression of SIRT3 disrupts mitochondrial proteostasis and cell cycle progressionSirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice.Sirtuin-3 (SIRT3) and the Hallmarks of Cancer.SIRT3 regulates cell proliferation and apoptosis related to energy metabolism in non-small cell lung cancer cells through deacetylation of NMNAT2Autophagy maintains ubiquitination-proteasomal degradation of Sirt3 to limit oxidative stress in K562 leukemia cells.Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer.Cancers with wrong HATs: the impact of acetylation.Metabolic regulation of Sirtuins upon fasting and the implication for cancerRedox control of enzymatic functions: The electronics of life's circuitry.Ionizing radiation-induced oxidative stress, epigenetic changes and genomic instability: the pivotal role of mitochondria.Intersections between mitochondrial sirtuin signaling and tumor cell metabolism.Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype.Mitochondrial Sirtuins and Molecular Mechanisms of Aging.SIRT3 inhibits cell proliferation in human gastric cancer through down-regulation of Notch-1.The Expression and Related Clinical Significance of SIRT3 in Non-Small-Cell Lung Cancer.Changes in sirtuin 2 and sirtuin 3 mRNA expressions in rheumatoid arthritis.SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells.SIRT3 Silencing Sensitizes Breast Cancer Cells to Cytotoxic Treatments Through an Increment in ROS Production.Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy.Ozone and SIRT3: an unexplored paradigm.Toxoplasma gondii GRA8 induces ATP5A1-SIRT3-mediated mitochondrial metabolic resuscitation: a potential therapy for sepsis.Decreased expression of sirtuin 3 protein correlates with early stage chronic renal allograft dysfunction in a rat kidney model.
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Metabolic regulation by SIRT3: implications for tumorigenesis.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Metabolic regulation by SIRT3: implications for tumorigenesis.
@en
type
label
Metabolic regulation by SIRT3: implications for tumorigenesis.
@en
prefLabel
Metabolic regulation by SIRT3: implications for tumorigenesis.
@en
P2860
P1476
Metabolic regulation by SIRT3: implications for tumorigenesis.
@en
P2093
Lydia W S Finley
Marcia C Haigis
P2860
P304
P356
10.1016/J.MOLMED.2012.05.004
P577
2012-06-27T00:00:00Z