Deoxyribonucleotide analogs as inhibitors and substrates of DNA polymerases.
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Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleasesCardiac dysfunction occurs in the HIV-1 transgenic mouse treated with zidovudineIn silico screening for novel inhibitors of DNA polymerase III alpha subunit of Mycobacterium tuberculosis (MtbDnaE2, H37Rv)Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase.Impact of 2-bromo-5,6-dichloro-1-beta-D-ribofuranosyl benzimidazole riboside and inhibitors of DNA, RNA, and protein synthesis on human cytomegalovirus genome maturation.Inhibitors of DNA polymerase III as novel antimicrobial agents against gram-positive eubacteria.In vitro antimicrobial activities of novel anilinouracils which selectively inhibit DNA polymerase III of gram-positive bacteria.Mitochondrial toxicity and HIV therapy.Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors.Properties of arabinonucleic acids (ANA & 20'F-ANA): implications for the design of antisense therapeutics that invoke RNase H cleavage of RNA.Analysis of inhibitors of bacteriophage T4 DNA polymerase.Expanding the repertoire of DNA polymerase substrates: template-instructed incorporation of non-nucleoside triphosphate analogues by DNA polymerases beta and lambdaAntibacterial activity and mechanism of action of a novel anilinouracil-fluoroquinolone hybrid compound.Architecture and conservation of the bacterial DNA replication machinery, an underexploited drug target.Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosidesThe molecular mechanism of inhibition of alpha-type DNA polymerases by N2-(butylphenyl)dGTP and 2-(butylanilino)dATP: variation in susceptibility to polymerization.Chemical and enzymatic incorporation of N2-(p-n-butylphenyl)-2'-deoxyguanosine into an oligodeoxyribonucleotide.The application of a modified nucleotide in aptamer selection: novel thrombin aptamers containing 5-(1-pentynyl)-2'-deoxyuridine.Mitochondrial DNA impairment in nucleoside reverse transcriptase inhibitor-associated cardiomyopathySelectivity of DNA polymerases toward alpha and beta nucleotide substrates of D and L series.DNA polymerase III of Mycoplasma pulmonis: isolation and characterization of the enzyme and its structural gene, polC.Synthesis and anti-Hantaan virus activity of N(1)-3-fluorophenyl-inosine.Mitochondrial toxicity of antiviral drugs.Purification and properties of DNA polymerase from Bacillus caldotenax.Kinetic studies with N2-phenylguanines and with L-thymidine indicate that herpes simplex virus type-1 thymidine kinase and thymidylate kinase share a common active site
P2860
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P2860
Deoxyribonucleotide analogs as inhibitors and substrates of DNA polymerases.
description
article científic
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article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Deoxyribonucleotide analogs as inhibitors and substrates of DNA polymerases.
@en
type
label
Deoxyribonucleotide analogs as inhibitors and substrates of DNA polymerases.
@en
prefLabel
Deoxyribonucleotide analogs as inhibitors and substrates of DNA polymerases.
@en
P1476
Deoxyribonucleotide analogs as inhibitors and substrates of DNA polymerases.
@en
P2093
P304
P356
10.1016/0163-7258(90)90066-B
P577
1990-01-01T00:00:00Z