Endoplasmic reticulum stress, pancreatic β-cell degeneration, and diabetes.
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Pancreatic β Cell Mass DeathEndoplasmic Reticulum Stress and Associated ROSMechanisms and models of endoplasmic reticulum stress in chondrodysplasiaEndoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseasesEndocrine Imbalance Associated With Proteome Changes in Diabetes.The Janus Head of Oxidative Stress in Metabolic Diseases and During Physical Exercise.Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish.Dermal wound transcriptomic responses to Infection with Pseudomonas aeruginosa versus Klebsiella pneumoniae in a rabbit ear wound model.Common therapeutic targets in cardiometabolic diseaseValproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells.Engineered VEGF-releasing PEG-MAL hydrogel for pancreatic islet vascularization.Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts.Established and emerging biomarkers for the prediction of type 1 diabetes: a systematic review.The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells.Protection of Human Pancreatic Islets from Lipotoxicity by Modulation of the TransloconInsulin demand regulates β cell number via the unfolded protein response.Circadian Disruption and Diet-Induced Obesity Synergize to Promote Development of β-Cell Failure and Diabetes in Male Rats.FGF1 Mediates Overnutrition-Induced Compensatory β-Cell DifferentiationPDIA6 regulates insulin secretion by selectively inhibiting the RIDD activity of IRE1.An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases.PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes.Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux.Npas4 is a novel activity-regulated cytoprotective factor in pancreatic β-cells.CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis.Sphingosine-1-phosphate Phosphatase 2 Regulates Pancreatic Islet β-Cell Endoplasmic Reticulum Stress and Proliferation.Cocaine induces astrocytosis through ER stress-mediated activation of autophagyEndoplasmic reticulum stress-unfolding protein response-apoptosis cascade causes chondrodysplasia in a col2a1 p.Gly1170Ser mutated mouse modelDiscovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic β-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress.Molecular pathways: emerging roles of mammalian Sirtuin SIRT7 in cancerLive or let die: posttranscriptional gene regulation in cell stress and cell death.Functional and morphological impact of ER stress on mitochondria.Targeting the pancreatic β-cell to treat diabetes.A molecular web: endoplasmic reticulum stress, inflammation, and oxidative stress.Druggable sensors of the unfolded protein response.CHOP Deficiency Ameliorates ERK5 Inhibition-Mediated Exacerbation of Streptozotocin-Induced Hyperglycemia and Pancreatic β-Cell Apoptosis.Identification of 1,2,3-triazole derivatives that protect pancreatic β cells against endoplasmic reticulum stress-mediated dysfunction and death through the inhibition of C/EBP-homologous protein expression.Temporal characterization of β cell-adaptive and -maladaptive mechanisms during chronic high-fat feeding in C57BL/6NTac mice.
P2860
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P2860
Endoplasmic reticulum stress, pancreatic β-cell degeneration, and diabetes.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Endoplasmic reticulum stress, pancreatic β-cell degeneration, and diabetes.
@en
type
label
Endoplasmic reticulum stress, pancreatic β-cell degeneration, and diabetes.
@en
prefLabel
Endoplasmic reticulum stress, pancreatic β-cell degeneration, and diabetes.
@en
P2860
P1476
Endoplasmic reticulum stress, pancreatic β-cell degeneration, and diabetes.
@en
P2093
Feroz R Papa
P2860
P304
P356
10.1101/CSHPERSPECT.A007666
P577
2012-09-01T00:00:00Z