Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase.
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Out of balance: R-loops in human diseaseTranscriptional stalling in B-lymphocytes: a mechanism for antibody diversification and maintenance of genomic integrityUnderstanding specific functions of PARP-2: new lessons for cancer therapyMolecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancerA PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complexChromosomal translocations and karyotype complexity in chronic lymphocytic leukemia: a systematic reappraisal of classic cytogenetic data.ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.Induction of homologous recombination between sequence repeats by the activation induced cytidine deaminase (AID) proteinEpstein-Barr virus (EBV)-associated epithelial and non-epithelial lesions of the oral cavity.Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.Mechanisms that can promote peripheral B-cell lymphoma in ATM-deficient mice.Evidence for APOBEC3B mutagenesis in multiple human cancersElevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancersPsoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.The AID-induced DNA damage response in chromatin.Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development.Epigenetic targeting of activation-induced cytidine deaminase.Engineered proteins detect spontaneous DNA breakage in human and bacterial cells.Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.Elevation of c-MYC disrupts HLA class II-mediated immune recognition of human B cell tumorsHuman lymphoid translocation fragile zones are hypomethylated and have accessible chromatin.Genomic uracil homeostasis during normal B cell maturation and loss of this balance during B cell cancer development.Splice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells.Cell Cycle Regulates Nuclear Stability of AID and Determines the Cellular Response to AID.What's the damage? The impact of pathogens on pathways that maintain host genome integrityThe Yin and Yang of R-loop biology.Plasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma.AID-expressing epithelium is protected from oncogenic transformation by an NKG2D surveillance pathway.Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma.Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching.Activation-induced Cytidine Deaminase in B Cell Immunity and Cancers.The origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity.Nucleic acid determinants for selective deamination of DNA over RNA by activation-induced deaminase.Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous CarcinogenesisUNG protects B cells from AID-induced telomere loss.APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.The cell cycle restricts activation-induced cytidine deaminase activity to early G1.Progress toward active or passive HIV-1 vaccination.Reactivation of dormant anti-tumor immunity - a clinical perspective of therapeutic immune checkpoint modulation.
P2860
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P2860
Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase.
@en
type
label
Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase.
@en
prefLabel
Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase.
@en
P1476
Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase.
@en
P2093
Davide F Robbiani
P304
P356
10.1146/ANNUREV-PATHOL-020712-164004
P577
2012-09-04T00:00:00Z