Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch. - Wikidata - awgldk - TriplyDB

Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch.

Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch.

http://www.wikidata.org/entity/Q38049051

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The notch ligand JAGGED1 as a target for anti-tumor therapy Novel agents for advanced pancreatic cancer Emerging roles of PDGF-D in EMT progression during tumorigenesis Wound healing and cancer stem cells: inflammation as a driver of treatment resistance in breast cancer Nrf2 and Notch Signaling in Lung Cancer: Near the Crossroad Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer.Clinical impact of de-regulated Notch-1 and Notch-3 in the development and progression of HPV-associated different histological subtypes of precancerous and cancerous lesions of human uterine cervix.Hedgehog signaling pathway in colorectal cancer: function, mechanism, and therapy.Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells SMO expression in colorectal cancer: associations with clinical, pathological, and molecular features Expression of the GLI family genes is associated with tumor progression in advanced lung adenocarcinoma.Nestin predicts a favorable prognosis in early ampullary adenocarcinoma and functions as a promoter of metastasis in advanced cancer.The roles of Notch3 on the cell proliferation and apoptosis induced by CHIR99021 in NSCLC cell lines: a functional link between Wnt and Notch signaling pathways Genome-wide microarray expression and genomic alterations by array-CGH analysis in neuroblastoma stem-like cells.Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002.Can we safely target the WNT pathway?Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity.Multi-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel Biomarkers Peritoneal expression of Matrilysin helps identify early post-operative recurrence of colorectal cancer.Chronic chemotherapeutic stress promotes evolution of stemness and WNT/beta-catenin signaling in colorectal cancer cells: implications for clinical use of WNT-signaling inhibitors.FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.Targeting the Notch pathway: A potential therapeutic approach for desmoid tumors Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer Increased LEF1 expression and decreased Notch2 expression are strong predictors of poor outcomes in colorectal cancer patients.Inhibition of cell proliferation and tumor growth of colorectal cancer by inhibitors of Wnt and Notch signaling pathways.GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment.Advanced glycosylation end product promotes forkhead box O1 and inhibits Wnt pathway to suppress capacities of epidermal stem cells.XTalkDB: a database of signaling pathway crosstalk.Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway.Oncogenic role and therapeutic target of leptin signaling in colorectal cancer.Sonic hedgehog signaling in Basal cell nevus syndrome.Pluripotency transcription factors in the pathogenesis of colorectal cancer and implications for prognosis.The Notch pathway in colorectal cancer.Oleic Acid Uptake Reveals the Rescued Enterocyte Phenotype of Colon Cancer Caco-2 by HT29-MTX Cells in Co-Culture Mode.BMP10 inhibited the growth and migration of gastric cancer cells.Notch-1 promotes stemness and epithelial to mesenchymal transition in colorectal cancer.SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell carcinoma.

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Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch.

http://www.wikidata.org/entity/Q38049051

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Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch.

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Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch.

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Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch.

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Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch.

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C William Angus

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Fred E Bertrand

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George Sigounas

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William J Partis

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P2860

TGF-beta signal transduction

Global cancer statistics

Two genetic hits (more or less) to cancer

Identification of c-MYC as a target of the APC pathway

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Comprehensive molecular characterization of human colon and rectal cancer

Wnt/β-catenin signaling and disease

A genetic model for colorectal tumorigenesis

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

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10.4161/CC.22134

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23

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2012-10-03T00:00:00Z

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23032367

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