The protein arginine deiminases: Structure, function, inhibition, and disease.
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Inhibitors of Serine Proteases in Regulating the Production and Function of Neutrophil Extracellular TrapsProtein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with DysregulationCitrullination in Rheumatoid Arthritis-A Process Promoted by Neutrophil Lysis?The quest for an effective and safe personalized cell therapy using epigenetic toolsFunctional decorations: post-translational modifications and heart disease delineated by targeted proteomics.Investigating citrullinated proteins in tumour cell linesThe Effects of Blast Exposure on Protein Deimination in the BrainA FluoPol-ABPP PAD2 high-throughput screen identifies the first calcium site inhibitor targeting the PADs.Peptidyl arginine deiminase-4 activation exacerbates kidney ischemia-reperfusion injury.A core MRB1 complex component is indispensable for RNA editing in insect and human infective stages of Trypanosoma brucei.Identification of multiple structurally distinct, nonpeptidic small molecule inhibitors of protein arginine deiminase 3 using a substrate-based fragment methodChemical biology of protein arginine modifications in epigenetic regulationProtein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.Peptidylarginine deiminase from Porphyromonas gingivalis contributes to infection of gingival fibroblasts and induction of prostaglandin E2 -signaling pathway.Inhibition of peptidylarginine deiminase attenuates inflammation and improves survival in a rat model of hemorrhagic shock.From sequence and forces to structure, function, and evolution of intrinsically disordered proteinsMolecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancerExtracellular traps and macrophages: new roles for the versatile phagocyte.A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22Autoimmunity to citrullinated proteins and the initiation of rheumatoid arthritisNeutrophil extracellular chromatin traps connect innate immune response to autoimmunity.Autoantigens: novel forms and presentation to the immune system.Applications of copper-catalyzed click chemistry in activity-based protein profiling.A novel role for protein arginine deiminase 4 in pluripotency: the emerging role of citrullinated histone H1 in cellular programming.Pluripotency: citrullination unravels stem cellsCitrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα.PAD4: pathophysiology, current therapeutics and future perspective in rheumatoid arthritis.A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma.Synovial fluid proteome in rheumatoid arthritis.The case for periodontitis in the pathogenesis of rheumatoid arthritis.The W620 Polymorphism in PTPN22 Disrupts Its Interaction With Peptidylarginine Deiminase Type 4 and Enhances Citrullination and NETosis.Peptidyl arginine deiminase-4-deficient mice are protected against kidney and liver injury after renal ischemia and reperfusion.Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors.Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils.Facile fluorescence-based detection of PAD4-mediated citrullination.Oxidative Modifications in Tissue Pathology and Autoimmune Disease.Affinity maturation shapes the function of agonistic antibodies to peptidylarginine deiminase type 4 in rheumatoid arthritis.ATP induces PAD4 in renal proximal tubule cells via P2X7 receptor activation to exacerbate ischemic AKI.Rheumatoid arthritis and citrullination.Theoretical insights into the protonation states of active site cysteine and citrullination mechanism of Porphyromonas gingivalis peptidylarginine deiminase.
P2860
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P2860
The protein arginine deiminases: Structure, function, inhibition, and disease.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
@es
name
The protein arginine deiminases: Structure, function, inhibition, and disease.
@en
type
label
The protein arginine deiminases: Structure, function, inhibition, and disease.
@en
prefLabel
The protein arginine deiminases: Structure, function, inhibition, and disease.
@en
P2860
P921
P356
P1433
P1476
The protein arginine deiminases: Structure, function, inhibition, and disease
@en
P2093
Paul R Thompson
P2860
P304
P356
10.1002/BIP.22127
P577
2013-02-01T00:00:00Z