Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis.
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pH sensing and regulation in cancerNitric oxide and pH modulation in gynaecological cancerGPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cellsTalin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis.Short-term adaptation of the ruminal epithelium involves abrupt changes in sodium and short-chain fatty acid transport.Regulation of invadopodia by the tumor microenvironment.Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer questionMicroenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy.A leak pathway for luminal protons in endosomes drives oncogenic signalling in glioblastomaA novel human mutation in the SLC9A1 gene results in abolition of Na+/H+ exchanger activity.The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cellsCancer as a channelopathy: ion channels and pumps in tumor development and progressionRhoA Kinase (Rock) and p90 Ribosomal S6 Kinase (p90Rsk) phosphorylation of the sodium hydrogen exchanger (NHE1) is required for lysophosphatidic acid-induced transport, cytoskeletal organization and migration.Stop Codon Polymorphisms in the Human SLC9A1 Gene Disrupt or Compromise Na+/H+ Exchanger FunctionAvian leukosis virus subgroup J induces its receptor--chNHE1 up-regulationNa(+) Micro-Current Value Detection as a New Modality for Identification of Benign and Malignant Disease in Surgery.pH sensing by FAK-His58 regulates focal adhesion remodelingNa+/H+ exchanger NHE1 regulation modulates metastatic potential and epithelial-mesenchymal transition of triple-negative breast cancer cells.Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research.Na+/H+ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma.Small molecule hormone or hormone-like ligands of integrin αVβ3: implications for cancer cell behavior.Role of pHi, and proton transporters in oncogene-driven neoplastic transformation.Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential.Targeting osteopontin, the silent partner of Na+/H+ exchanger isoform 1 in cardiac remodeling.Glioma-mediated microglial activation promotes glioma proliferation and migration: roles of Na+/H+ exchanger isoform 1.Functional interdependence of NHE1 and merlin in human melanoma cells.Characterization of human mutations in phosphorylatable amino acids of the cytosolic regulatory tail of SLC9A1.Of channels and pumps: different ways to boost the aldosterone?Determinants of Cation Permeation and Drug Sensitivity in Predicted Transmembrane Helix 9 and Adjoining Exofacial Re-entrant Loop 5 of Na+/H+ Exchanger NHE1.Molecular machineries of pH dysregulation in tumor microenvironment: potential targets for cancer therapyNHE1 has a notable role in metastasis and drug resistance of T-cell acute lymphoblastic leukemia.Extracellular protonation modulates cell-cell interaction mechanics and tissue invasion in human melanoma cells.Transmembrane Segment XI of the Na+/H+ Antiporter of S. pombe is a Critical Part of the Ion Translocation Pore.Endothelial Ca2+ Signaling and the Resistance to Anticancer Treatments: Partners in Crime.The interactome and spatial redistribution feature of Ca2+ receptor protein calmodulin reveals a novel role in invadopodia-mediated invasion.Label-free detection of pH based on the i-motif using an aggregation-caused quenching strategy.TOR complex 1 regulates the yeast plasma membrane proton pump and pH and potassium homeostasis.The Fight Against Cancer: Nitrobenzaldehyde as the Potential Warrior.Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases.Assessing Na+/H+ exchange and cell effector functionality in metastatic breast cancer.
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Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis.
@en
type
label
Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis.
@en
prefLabel
Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis.
@en
P1433
P1476
Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis.
@en
P2093
Schammim R Amith
P304
P356
10.1158/0008-5472.CAN-12-4031
P407
P577
2013-02-07T00:00:00Z