Alternative lengthening of telomeres: remodeling the telomere architecture.
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Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome MaintenanceNew players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperoneTelomere elongation chooses TERRA ALTernativesGenetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma CellsEpigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas.Telomere maintenance mechanisms in cancer: clinical implicationsRNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells.The role of double-strand break repair pathways at functional and dysfunctional telomeres.CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells.Identification of telomere dysfunction in Friedreich ataxiaCoffee provides a natural multitarget pharmacopeia against the hallmarks of cancer.Internal genomic regions mobilized for telomere maintenance in C. elegans.Telomeric RNAs are essential to maintain telomeres.Nature vs nurture: interplay between the genetic control of telomere length and environmental factors.Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes.G-quadruplex structures in the human genome as novel therapeutic targets.Biology of telomeres: lessons from budding yeast.How homologous recombination maintains telomere integrity.Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integrityDiffusely infiltrating astrocytomas: pathology, molecular mechanisms and markers.Getting it done at the ends: Pif1 family DNA helicases and telomeres.NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination.The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children.Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss.Genome-wide studies of telomere biology in budding yeastCancer Cells with Alternative Lengthening of Telomeres Do Not Display a General Hypersensitivity to ATR Inhibition.A new role for human dyskerin in vesicular trafficking.Mathematical model of alternative mechanism of telomere length maintenance.TERT promoter mutations rather than methylation are the main mechanism for TERT upregulation in adult gliomas.Differential nuclear ATRX expression in sarcomas.Break induced replication in eukaryotes: mechanisms, functions, and consequences.Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism.A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes
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P2860
Alternative lengthening of telomeres: remodeling the telomere architecture.
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article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Alternative lengthening of telomeres: remodeling the telomere architecture.
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type
label
Alternative lengthening of telomeres: remodeling the telomere architecture.
@en
prefLabel
Alternative lengthening of telomeres: remodeling the telomere architecture.
@en
P2860
P356
P1476
Alternative lengthening of telomeres: remodeling the telomere architecture.
@en
P2093
Dimitri Conomos
Hilda A Pickett
P2860
P356
10.3389/FONC.2013.00027
P577
2013-02-20T00:00:00Z