RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells. - Wikidata - awgldk - TriplyDB

RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells.

RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells.

http://www.wikidata.org/entity/Q34446552

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Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies Telomere biology: Rationale for diagnostics and therapeutics in cancer Telomere elongation chooses TERRA ALTernatives Alternative lengthening of telomeres can be maintained by preferential elongation of lagging strands.Trypanosoma brucei RAP1 maintains telomere and subtelomere integrity by suppressing TERRA and telomeric RNA:DNA hybrids Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1 Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes.Differential requirements for DNA repair proteins in immortalized cell lines using alternative lengthening of telomere mechanisms.TERRA promotes telomerase-mediated telomere elongation in Schizosaccharomyces pombe Telomeric RNAs are essential to maintain telomeres.Transcription of telomeric DNA leads to high levels of homologous recombination and t-loops.Nuclear Noncoding RNAs and Genome Stability.Genome maintenance and bioenergetics of the long-lived hypoxia-tolerant and cancer-resistant blind mole rat, Spalax: a cross-species analysis of brain transcriptome.Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids Stop pulling my strings - what telomeres taught us about the DNA damage response.Chromatin dynamics of plant telomeres and ribosomal genes.Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integrity Genetic and epigenetic trends in telomere research: a novel way in immunoepigenetics.Human Ribonuclease H1 resolves R loops and thereby enables progression of the DNA replication fork.The chromatin remodelling factor ATRX suppresses R-loops in transcribed telomeric repeats.R-loop: an emerging regulator of chromatin dynamics.Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX.Nascent Connections: R-Loops and Chromatin Patterning.Convergence of The Nobel Fields of Telomere Biology and DNA Repair.Non-Canonical Replication Initiation: You're Fired!Solving the Telomere Replication Problem.DNA Replication Origins and Fork Progression at Mammalian Telomeres Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes.Telomere Transcripts Target Telomerase in Human Cancer Cells.The crosstalk of telomere dysfunction and inflammation through cell-free TERRA containing exosomes.ALTernative Telomere Maintenance and Cancer.Regulation of telomere metabolism by the RNA processing protein Xrn1.The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression.Diagnosis and treatment of ALT tumors: is Trabectedin a new therapeutic option?CTCF driven TERRA transcription facilitates completion of telomere DNA replication.The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage.Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA.Dynamic nucleoplasmic and nucleolar localization of mammalian RNase H1 in response to RNAP I transcriptional R-loops.Telomeres, Aging and Exercise: Guilty by Association?

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P2860

RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells.

http://www.wikidata.org/entity/Q34446552

description

2014 nî lūn-bûn

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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

RNaseH1 regulates TERRA-telome ...... intenance in ALT tumour cells.

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RNaseH1 regulates TERRA-telome ...... intenance in ALT tumour cells.

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RNaseH1 regulates TERRA-telome ...... intenance in ALT tumour cells.

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type

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RNaseH1 regulates TERRA-telome ...... intenance in ALT tumour cells.

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RNaseH1 regulates TERRA-telome ...... intenance in ALT tumour cells.

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RNaseH1 regulates TERRA-telome ...... intenance in ALT tumour cells.

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RNaseH1 regulates TERRA-telome ...... intenance in ALT tumour cells.

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RNaseH1 regulates TERRA-telome ...... intenance in ALT tumour cells.

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RNaseH1 regulates TERRA-telome ...... intenance in ALT tumour cells.

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Nature Communications

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RNaseH1 regulates TERRA-telome ...... aintenance in ALT tumour cells

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Catherine M Brun

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Harry Wischnewski

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Tobias Schwarz

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P2860

Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres

Human UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replication

The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends

TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres

How shelterin protects mammalian telomeres

RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.

Role of alternative telomere lengthening unmasked in telomerase knock-out mutant plants.

Mechanisms of genome instability induced by RNA-processing defects.

Telomeres: protecting chromosomes against genome instability

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10.1038/NCOMMS6220

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5

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Claus M. Azzalin

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4218956

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