Fasudil and its analogs: a new powerful weapon in the long war against central nervous system disorders? - Wikidata - awgldk - TriplyDB

Fasudil and its analogs: a new powerful weapon in the long war against central nervous system disorders?

Fasudil and its analogs: a new powerful weapon in the long war against central nervous system disorders?

http://www.wikidata.org/entity/Q38086608

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A new in vitro mouse oligodendrocyte precursor cell migration assay reveals a role for integrin-linked kinase in cell motility Fasudil alleviates traumatic optic neuropathy by inhibiting Rho signaling pathway.The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia.Mechanisms, treatment and prevention of cellular injury and death from delayed events after aneurysmal subarachnoid hemorrhage.Rho Kinase and Dopaminergic Degeneration: A Promising Therapeutic Target for Parkinson's Disease.Chatting with the neighbors: crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders.Nonbiological pharmacotherapies for the treatment of diabetic macular edema.Interaction between NADPH-oxidase and Rho-kinase in angiotensin II-induced microglial activation.Quantitative Phosphoproteomics Reveals a Role for Collapsin Response Mediator Protein 2 in PDGF-Induced Cell Migration.Combined treatment of fasudil and glutamate decreased the viability of human glioblastoma cells by excitotoxicity through NMDAR in vitro Effect of N-arachidonoyl-l-serine on human cerebromicrovascular endothelium.Combination treatment with fasudil and clioquinol produces synergistic anti-tumor effects in U87 glioblastoma cells by activating apoptosis and autophagy.Fasudil inhibits LPS-induced migration of retinal microglial cells via regulating p38-MAPK signaling pathway.Induction of oligodendrocyte differentiation and in vitro myelination by inhibition of rho-associated kinase.Targeting the RhoA-ROCK pathway to reverse T-cell dysfunction in SLE.Selective activation of vascular Kv 7.4/Kv 7.5 K+ channels by fasudil contributes to its vasorelaxant effect.Vasodilatory effect of a novel Rho-kinase inhibitor, DL0805-2, on the rat mesenteric artery and its potential mechanisms.Fasudil, a Rho-Kinase Inhibitor, Exerts Cardioprotective Function in Animal Models of Myocardial Ischemia/Reperfusion Injury: A Meta-Analysis and Review of Preclinical Evidence and Possible Mechanisms

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P2860

Fasudil and its analogs: a new powerful weapon in the long war against central nervous system disorders?

http://www.wikidata.org/entity/Q38086608

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13543784.2013.778242

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Expert Opinion on Investigational Drugs

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Fasudil and its analogs: a new ...... tral nervous system disorders?

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Anmin Liu

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Meihui Chen

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Rongbiao Pi

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Xiaojuan Chao

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Ying Ouyang

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Yingjuan Huang

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P2860

Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase

Rocks: multifunctional kinases in cell behaviour

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity

A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)

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537-550

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10.1517/13543784.2013.778242

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22

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2013-03-05T00:00:00Z

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235795868

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23461757

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