TARDBP and FUS mutations associated with amyotrophic lateral sclerosis: summary and update.
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From animal models to human disease: a genetic approach for personalized medicine in ALSMechanisms of FUS mutations in familial amyotrophic lateral sclerosisMitochondria-associated membranes as hubs for neurodegenerationFUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysisModeling ALS and FTD with iPSC-derived neuronsMotor neuron derivation from human embryonic and induced pluripotent stem cells: experimental approaches and clinical perspectivesConverging mechanisms in ALS and FTD: disrupted RNA and protein homeostasisExploring new pathways of neurodegeneration in ALS: the role of mitochondria quality controlFUS Interacts with HSP60 to Promote Mitochondrial DamageNovel Neuroprotective Multicomponent Therapy for Amyotrophic Lateral Sclerosis Designed by Networked SystemsFUS is sequestered in nuclear aggregates in ALS patient fibroblasts.Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasmALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation.CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs.Serum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS).Absence of mutations in exon 6 of the TARDBP gene in 207 Chinese patients with sporadic amyotrohic lateral sclerosisAberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets?Expression of FSHD-related DUX4-FL alters proteostasis and induces TDP-43 aggregationUBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination.Familial behavioral variant frontotemporal dementia associated with astrocyte-predominant tauopathyIntermediate CAG repeat expansion in the ATXN2 gene is a unique genetic risk factor for ALS--a systematic review and meta-analysis of observational studies.A fruitful endeavor: modeling ALS in the fruit flyRegulation of human MAPT gene expression.Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain.Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.Defining the spectrum of frontotemporal dementias associated with TARDBP mutations.Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic AggregatesNeuromuscular Junction Impairment in Amyotrophic Lateral Sclerosis: Reassessing the Role of Acetylcholinesterase.Proteomics strategies to identify SUMO targets and acceptor sites: a survey of RNA-binding proteins SUMOylation.Minor splicing pathway is not minor any more: implications for the pathogenesis of motor neuron diseases.RNA binding proteins: a common denominator of neuronal function and dysfunction.Fishing for causes and cures of motor neuron disorders.Genetic causes of amyotrophic lateral sclerosis: new genetic analysis methodologies entailing new opportunities and challenges.Invited review: decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art.Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model.Old versus New Mechanisms in the Pathogenesis of ALS.Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins.Simple animal models for amyotrophic lateral sclerosis drug discovery.Pathogenesis of amyotrophic lateral sclerosis.Genetic Characterization of a French Cohort of GNE-mutation negative inclusion body myopathy patients with exome sequencing.
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TARDBP and FUS mutations associated with amyotrophic lateral sclerosis: summary and update.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
TARDBP and FUS mutations assoc ...... sclerosis: summary and update.
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type
label
TARDBP and FUS mutations assoc ...... sclerosis: summary and update.
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prefLabel
TARDBP and FUS mutations assoc ...... sclerosis: summary and update.
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P2860
P356
P1433
P1476
TARDBP and FUS mutations assoc ...... sclerosis: summary and update.
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P2093
Edor Kabashi
Serena Lattante
P2860
P304
P356
10.1002/HUMU.22319
P577
2013-04-29T00:00:00Z