Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives.

Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives.

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http://www.wikidata.org/entity/Q38103907
A repurposing strategy for Hsp90 inhibitors demonstrates their potency against filarial nematodesHsp90 regulation of fibroblast activation in pulmonary fibrosis.A physiologically based pharmacokinetic model of alvespimycin in mice and extrapolation to rats and humans.Heat shock protein 90 inhibition by 17-DMAG attenuates abdominal aortic aneurysm formation in miceY-632 inhibits heat shock protein 90 (Hsp90) function by disrupting the interaction between Hsp90 and Hsp70/Hsp90 organizing protein, and exerts antitumor activity in vitro and in vivoA "Double-Edged" Scaffold: Antitumor Power within the Antibacterial Quinolone.Alterations in the rat serum proteome induced by prepubertal exposure to bisphenol a and genistein.Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO13-Oxyingenol dodecanoate, a cytotoxic ingenol derivative, induces mitochondrial apoptosis and caspase-dependent Akt decrease in K562 cells.Combination of traditional mutation and metabolic engineering to enhance ansamitocin P-3 production in Actinosynnema pretiosum.Regulation of the Tumor-Suppressor BECLIN 1 by Distinct Ubiquitination Cascades.17-Demethoxy-reblastatin, an Hsp90 inhibitor, induces mitochondria-mediated apoptosis through downregulation of Mcl-1 in human hepatocellular carcinoma cells.Metabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes.The Nuclear Receptor Field: A Historical Overview and Future Challenges
P2860

Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives.

Item
http://www.wikidata.org/entity/Q38103907
description
article científic
@ca
article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Discovery and development of h ...... tent geldanamycin derivatives.
@en
type
label
Discovery and development of h ...... tent geldanamycin derivatives.
@en
prefLabel
Discovery and development of h ...... tent geldanamycin derivatives.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Discovery and development of h ...... tent geldanamycin derivatives.
@en
P2093
P2860
P304
P31
P356
10.1517/13543776.2013.780597
P407
P433
P478
P577
P698
P921