Repositioning metformin for cancer prevention and treatment.
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Unexploited Antineoplastic Effects of Commercially Available Anti-Diabetic DrugsChemoprevention of cancer: current evidence and future prospectsPAS kinase: a nutrient sensing regulator of glucose homeostasis.Heterogeneity of glycolysis in cancers and therapeutic opportunities.Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer.The antitumor effects of geraniol: Modulation of cancer hallmark pathways (Review)The Warburg effect: 80 years onMolecular Connections between Cancer Cell Metabolism and the Tumor MicroenvironmentMetformin as a new anti-cancer drug in adrenocortical carcinomaDeciphering Signaling Pathway Networks to Understand the Molecular Mechanisms of Metformin ActionMetformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent BiosynthesisA survey of current trends in computational drug repositioningDo metformin a real anticarcinogen? A critical reappraisal of experimental data.Metformin exhibits the anti-proliferation and anti-invasion effects in hepatocellular carcinoma cells after insufficient radiofrequency ablationCGRRF1 as a novel biomarker of tissue response to metformin in the context of obesityNovel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus.mTORC2 activity in brain cancer: Extracellular nutrients are required to maintain oncogenic signaling.Oxidants and antioxidants in metabolic syndrome and cancer.Metformin in cancer prevention and therapy.Effects of metformin on retinoblastoma growth in vitro and in vivo.Effects of metformin, buformin, and phenformin on the post-initiation stage of chemically induced mammary carcinogenesis in the rat.Metformin inhibits cell growth by upregulating microRNA-26a in renal cancer cells.Ovarian tumor-initiating cells display a flexible metabolismMetformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma.Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion currentPAS kinase is activated by direct SNF1-dependent phosphorylation and mediates inhibition of TORC1 through the phosphorylation and activation of Pbp1The biology of castration-resistant prostate cancerSurvival of patients with stage IV lung cancer with diabetes treated with metformin.In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumorsUse of noninsulin anti diabetics for prevention and treatment of cancer- narrative review article.Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma.Disulfiram/copper-disulfiram Damages Multiple Protein Degradation and Turnover Pathways and Cytotoxicity is Enhanced by Metformin in Oesophageal Squamous Cell Carcinoma Cell Lines.Propranolol Reduces Cancer Risk: A Population-Based Cohort Study.Therapeutic Effects of Repurposed Therapies in Non-Small Cell Lung Cancer: What Is Old Is New Again.Pharmacologic screens reveal metformin that suppresses GRP78-dependent autophagy to enhance the anti-myeloma effect of bortezomib.Metformin Inhibits P. gingivalis Lipopolysaccharide (LPS)-influenced Inflammatory Response in Human Gingival Fibroblasts via Regulating Activating Transcription Factor-3 (ATF3) Expression.A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line modelsThe Impact of Diabetes Mellitus and Metformin Treatment on Survival of Patients with Advanced Pancreatic Cancer Undergoing ChemotherapyThe Impact of Diabetes on Gynecologic Cancer: Current Status and Future Directions.Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo.
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P2860
Repositioning metformin for cancer prevention and treatment.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
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name
Repositioning metformin for cancer prevention and treatment.
@en
type
label
Repositioning metformin for cancer prevention and treatment.
@en
prefLabel
Repositioning metformin for cancer prevention and treatment.
@en
P2093
P1476
Repositioning metformin for cancer prevention and treatment.
@en
P2093
Brendan J Quinn
Hiroshi Kitagawa
Joell J Gills
Phillip A Dennis
Regan M Memmott
P304
P356
10.1016/J.TEM.2013.05.004
P577
2013-06-15T00:00:00Z