Genetically humanized mouse models of drug metabolizing enzymes and transporters and their applications.
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Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical ModelsPreclinical mouse cancer models: a maze of opportunities and challenges.In vivo and in vitro metabolites from the main diester and monoester diterpenoid alkaloids in a traditional chinese herb, the aconitum speciesTransgenic mice and metabolomics for study of hepatic xenobiotic metabolism and toxicityIn Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice.Novel pre-clinical methodologies for pharmacokinetic drug-drug interaction studies: spotlight on "humanized" animal models.Validation of ion channel targets.Mouse models for pre-clinical drug testing in leukemia.Aryl hydrocarbon receptor (AHR): "pioneer member" of the basic-helix/loop/helix per-Arnt-sim (bHLH/PAS) family of "sensors" of foreign and endogenous signals.Serum serotonin reduced the expression of hepatic transporter Mrp2 and P-gp via regulating nuclear receptor CAR in PI-IBS rats.From bench to patient: model systems in drug discoverySpecies Differences in Human and Rodent PEPT2-Mediated Transport of Glycylsarcosine and Cefadroxil in Pichia Pastoris Transformants.Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans.Humanizing the zebrafish liver shifts drug metabolic profiles and improves pharmacokinetics of CYP3A4 substrates.
P2860
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P2860
Genetically humanized mouse models of drug metabolizing enzymes and transporters and their applications.
description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Genetically humanized mouse mo ...... orters and their applications.
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type
label
Genetically humanized mouse mo ...... orters and their applications.
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prefLabel
Genetically humanized mouse mo ...... orters and their applications.
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P2860
P1433
P1476
Genetically humanized mouse mo ...... orters and their applications.
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P2093
C Roland Wolf
Nico Scheer
P2860
P304
P356
10.3109/00498254.2013.815831
P407
P577
2013-07-11T00:00:00Z